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NCT05140148 · ClinicalTrials.gov registry record · Phase 2

Promoting Recovery After STroke With Amantadine

A Phase 2 study of Stroke, Ischemic and Stroke Hemorrhagic, sponsored by University of Pennsylvania.

Recruiting
Registry status
Phase 2
Development phase
60
Enrollment target
1
Study location

NCT05140148 is a Phase 2 study of Stroke, Ischemic and Stroke Hemorrhagic that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 60 participants, below the 288-participant average among 33 other Stroke, Ischemic trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05140148, a Phase 2 study of Stroke, Ischemic and Stroke Hemorrhagic, is actively recruiting participants, sponsored by University of Pennsylvania.

RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The investigators aim to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial (RCT). Patients will be randomized post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine arm. Patients will be on study drug or placebo for 1 month but will be enrolled for 3 months total. At various time points patients will be examined and fill out questionnaires to determine level of stroke recovery.

Conditions Studied

Stroke, Ischemic Stroke Hemorrhagic

Interventions

  • DRUG Placebo
  • DRUG Amantadine

Study Locations (1)

Pennsylvania

  • The Hospital of the University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2022-02-01
Est. Completion 2026-06-30
Phase Phase 2

Sponsor

University of Pennsylvania

1,423 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05140148

The ClinicalTrials.gov registry entry for NCT05140148 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 288-participant average among 33 other Stroke, Ischemic trials with a reported enrollment target (79% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Stroke, Ischemic appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05140148 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT05140148 about?

NCT05140148 is a clinical study titled "Promoting Recovery After STroke With Amantadine". The investigators aim to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial (RCT). Patients will be randomized post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine arm. Patients will be on study drug or placebo fo...

What is the current status of trial NCT05140148?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2022-02-01. Estimated completion is 2026-06-30.

What conditions does trial NCT05140148 study?

This clinical trial studies the following conditions: Stroke, Ischemic, Stroke Hemorrhagic.

What interventions are being tested in trial NCT05140148?

The interventions under investigation include: Placebo (DRUG), Amantadine (DRUG).

Who is sponsoring clinical trial NCT05140148?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05140148 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.