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NCT05140148 · ClinicalTrials.gov registry record · Phase 2
Promoting Recovery After STroke With Amantadine
A Phase 2 study of Stroke, Ischemic and Stroke Hemorrhagic, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05140148: Recruiting Phase 2 study of Stroke, Ischemic and Stroke Hemorrhagic, sponsored by University of Pennsylvania.
NCT05140148 is a Phase 2 study of Stroke, Ischemic and Stroke Hemorrhagic that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 60 participants, below the 288-participant average among 33 other Stroke, Ischemic trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05140148, a Phase 2 study of Stroke, Ischemic and Stroke Hemorrhagic, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators aim to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial (RCT). Patients will be randomized post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine arm. Patients will be on study drug or placebo for 1 month but will be enrolled for 3 months total. At various time points patients will be examined and fill out questionnaires to determine level of stroke recovery.
Primary Outcome
Tolerability of the study drug will be assessed based on the proportion of patients who adherent with at least 80% of study medication.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Amantadine
Study Locations (1)
Pennsylvania
- The Hospital of the University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2022-02-01 |
| Est. Completion | 2026-06-30 |
| Phase | Phase 2 |
What NCT05140148 shows while recruiting
NCT05140148 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 288-participant average among 33 other Stroke, Ischemic trials with a reported enrollment target (79% lower).
The record links to 2 conditions, with Stroke, Ischemic appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05140148 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05140148 about?
NCT05140148 is a clinical study titled "Promoting Recovery After STroke With Amantadine". The investigators aim to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial (RCT). Patients will be randomized post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine arm. Patients will be on study drug or placebo fo...
What is the current status of trial NCT05140148?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2022-02-01. Estimated completion is 2026-06-30.
What conditions does trial NCT05140148 study?
This clinical trial studies the following conditions: Stroke, Ischemic, Stroke Hemorrhagic.
What interventions are being tested in trial NCT05140148?
The interventions under investigation include: Placebo (DRUG), Amantadine (DRUG).
Who is sponsoring clinical trial NCT05140148?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05140148 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke, Ischemic
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05140148's enrollment target sits among peer trials
60 18th of 33 higher than 13 of 33 other Stroke, Ischemic trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke, Ischemic trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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