Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05115890 · ClinicalTrials.gov registry record · NA

Muscle Blood Flow Regulation in HFpEF

A NA study of HFpEF, sponsored by VA Office of Research and Development.

Recruiting
Registry status
NA
Development phase
35
Enrollment target
1
Study location

NCT05115890: Recruiting NA study of HFpEF, sponsored by VA Office of Research and Development.

NCT05115890 is a NA study of HFpEF that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 35 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05115890, a NA study of HFpEF, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
NA
Development phase
35 participants
Enrollment target
1
Study location

Study Summary

Heart failure with preserved ejection (HFpEF) disproportionately affects Veterans and is the number one reason for hospital discharge in the VA Health Care System. Exercise intolerance is a common complication experienced by patients with HFpEF, perpetuating physical inactivity and accelerating disease progression. This research proposal aims to elucidate mechanisms responsible for inadequate skeletal muscle blood flow and exercise intolerance in patients with HFpEF compared with healthy controls as well as following 8 weeks of exercise training in patients with HFpEF only.

Primary Outcome

The six-minute walk test is used to measure distance covered during walking at a comfortable speed for six minutes

Conditions Studied

Interventions

  • OTHER Exercise training

Study Locations (1)

Utah

  • VA Salt Lake City Health Care System, Salt Lake City, UT - Salt Lake City

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2022-07-01
Est. Completion 2028-02-29
Phase NA
VA Office of Research and Development

1,668 total trials

What NCT05115890 shows while recruiting

NCT05115890 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 1 condition, with HFpEF appearing as the primary indexed condition, and to 1 intervention - of which Exercise training is the first listed.

NCT05115890 reports a single indexed study location in Utah.

Frequently Asked Questions

What is clinical trial NCT05115890 about?

NCT05115890 is a clinical study titled "Muscle Blood Flow Regulation in HFpEF". Heart failure with preserved ejection (HFpEF) disproportionately affects Veterans and is the number one reason for hospital discharge in the VA Health Care System. Exercise intolerance is a common complication experienced by patients with HFpEF, perpetuating physical inactivity and accelerating dise...

What is the current status of trial NCT05115890?

This trial is currently recruiting. It is a NA study. The enrollment target is 35 participants. The study started on 2022-07-01. Estimated completion is 2028-02-29.

What conditions does trial NCT05115890 study?

This clinical trial studies the following conditions: HFpEF.

What interventions are being tested in trial NCT05115890?

The interventions under investigation include: Exercise training (OTHER).

Who is sponsoring clinical trial NCT05115890?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05115890 being conducted?

This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT05115890's enrollment target sits among peer trials

35 1564th of 2000 higher than 431 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01697371 · 35 participants · NA

    Proton Therapy in the Treatment of Liver Metastases

  • NCT01940757 · 35 participants · Phase 1

    Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae

  • NCT02235857 · 35 participants · NA

    Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

  • NCT02637934 · 35 participants · Phase 1

    Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05115890, the US trial registry maintained by the National Library of Medicine. NCT05115890 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.