Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

Ferric Citrate for the Prevention of Renal Failure in Adults With Advanced Chronic Kidney Disease

NCT05085275 · View on ClinicalTrials.gov ↗

Study Summary

A 9-month randomized, double-blind, placebo-controlled study to compare the effect of fixed dose ferric citrate versus placebo in patients with advanced chronic kidney disease (eGFR ≤20 ml/min/1.73m2) on the composite endpoint of time to initiation of maintenance dialysis or all-cause mortality.

Interventions

  • DRUG Placebo
  • DRUG Ferric Citrate 1 GM Oral Tablet [AURYXIA]

Study Locations (20)

California

  • Balboa Research SMO — Chula Vista
  • Balboa Research SMO — El Centro
  • Balboa Research SMO — Escondido
  • Balboa Research SMO — La Mesa
  • Balboa Research SMO - Kearney Mesa — San Diego

Texas

  • South Texas Renal Care Group — Live Oak
  • South Texas Renal Care Group — San Antonio
  • South Texas Renal Care Group — San Antonio

Georgia

  • Dialysis Clinic, Inc. — Albany
  • Nephrology and Hypertension Specialists, PC — Dalton

Arkansas

  • Arkansas Nephrology & Hypertension Clinic — Pine Bluff

Colorado

  • Rocky Mountain Kidney Care — Lone Tree

Florida

  • Associates in Nephrology — Fort Myers

Indiana

  • Major Health Partners — Shelbyville

Missouri

  • Kidney Associates of Kansas City — Kansas City

Trial Details

FieldValue
Enrollment Target 289 participants
Start Date 2022-03-30
Est. Completion 2024-01-24
Phase Phase 3

Sponsor

USRC Kidney Research

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05085275

The ClinicalTrials.gov registry entry for NCT05085275 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 289 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is USRC Kidney Research, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 7 conditions, with Renal Insufficiency, Chronic appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05085275 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, Texas, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05085275 about?

NCT05085275 is a clinical study titled "Ferric Citrate for the Prevention of Renal Failure in Adults With Advanced Chronic Kidney Disease". A 9-month randomized, double-blind, placebo-controlled study to compare the effect of fixed dose ferric citrate versus placebo in patients with advanced chronic kidney disease (eGFR ≤20 ml/min/1.73m2) on the composite endpoint of time to initiation of maintenance dialysis or all-cause mortality.

What is the current status of trial NCT05085275?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 289 participants. The study started on 2022-03-30. Estimated completion is 2024-01-24.

What conditions does trial NCT05085275 study?

This clinical trial studies the following conditions: Renal Insufficiency, Chronic, Cardiovascular, Hyperphosphatemia, Anemia, Iron Deficiency, Disease Progression. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05085275?

The interventions under investigation include: Placebo (DRUG), Ferric Citrate 1 GM Oral Tablet [AURYXIA] (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05085275?

This trial is sponsored by USRC Kidney Research, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05085275 being conducted?

This trial has 20 study locations across Arkansas, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial