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ACTIVE NOT RECRUITING Phase 2

Amivantamab in Adenoid Cystic Carcinoma

NCT05074940 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of the study is to determine if treatment with amivantamab will be efficacious in patients with recurrent and metastatic adenoid cystic carcinoma.

Conditions Studied

Interventions

  • DRUG Amivantamab

Study Locations (5)

California

  • UC San Diego Moores Cancer Center — La Jolla

Massachusetts

  • Dana Farber Cancer Institute — Boston

Michigan

  • Rogel Cancer Center - University of Michigan Health — Ann Arbor

Missouri

  • Washington University - School of Medicine in St. Louis — St Louis

Ohio

  • University of Cincinnati Medical Center — Cincinnati

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2022-08-05
Est. Completion 2028-08-05
Phase Phase 2

Sponsor

Trisha Wise-Draper

5 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05074940

The ClinicalTrials.gov registry entry for NCT05074940 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Trisha Wise-Draper, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Salivary Gland Cancer appearing as the primary indexed condition, and to 1 intervention — of which Amivantamab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05074940 reports 5 study locations spanning 5 distinct geographic areas — top geographies include California, Massachusetts, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05074940 about?

NCT05074940 is a clinical study titled "Amivantamab in Adenoid Cystic Carcinoma". The purpose of the study is to determine if treatment with amivantamab will be efficacious in patients with recurrent and metastatic adenoid cystic carcinoma.

What is the current status of trial NCT05074940?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2022-08-05. Estimated completion is 2028-08-05.

What conditions does trial NCT05074940 study?

This clinical trial studies the following conditions: Salivary Gland Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05074940?

The interventions under investigation include: Amivantamab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05074940?

This trial is sponsored by Trisha Wise-Draper, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05074940 being conducted?

This trial has 5 study locations across California, Massachusetts, Michigan, Missouri, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial