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NCT05073471 · ClinicalTrials.gov registry record · NA
Music and Brain Stimulation for Upper Extremity Performance in Patients With Corticobasal Syndrome
A NA study of Corticobasal Syndrome and Upper Extremity Dysfunction, sponsored by Johns Hopkins University.
- Active
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05073471: Active NA study of Corticobasal Syndrome and Upper Extremity Dysfunction, sponsored by Johns Hopkins University.
NCT05073471 is a NA study of Corticobasal Syndrome and Upper Extremity Dysfunction that is active but no longer recruiting, run by Johns Hopkins University. The registered enrollment target is 20 participants, below the 304-participant average among 6 other Corticobasal Syndrome trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05073471, a NA study of Corticobasal Syndrome and Upper Extremity Dysfunction, is active but no longer recruiting, sponsored by Johns Hopkins University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is designed to investigate how musical patterns (e.g., patterned sensory enhancement, PSE) and non-invasive brain stimulation (e.g., transcranial direct current stimulation, tDCS) are effective to improve functional upper extremity performances in patients with corticobasal syndrome (CBS). 20 individuals with CBS will be randomly assigned to either PSE group (n= 10) or PSE+tDCS (n=10) group. Both interventions are 30 minutes long, twice a week for three weeks (a total of 6 sessions). Participants' self-reported and measurable outcomes including upper extremity function, kinematic quantities, quality of life, mood, cognitive level, and brain activity (e.g. electroencephalography, EEG) will be assessed in the baseline, pre- and post- each session, and follow-up phase. This study seeks to assess the possibility that music-based intervention and non-invasive brain stimulation may improve outcomes in CBS patients for patients' non-invasive but cost-effective rehabilitation settings in the future.
Primary Outcome
Wolf Motor Function Test (WMFT) is a quantitative index of upper extremity motor ability examinable through the use of timed and functional tasks. The maximum score is 72, and lower scores are indicative of lower functioning levels.
Conditions Studied
Interventions
- DEVICE Transcranial Direct Current Stimulation (tDCS)
- BEHAVIORAL Patterned Sensory Enhancement (PSE)
Study Locations (1)
Maryland
- Johns Hopkins School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-04-22 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What the registry record for NCT05073471 still lists
NCT05073471 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 304-participant average among 6 other Corticobasal Syndrome trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Corticobasal Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Transcranial Direct Current Stimulation (tDCS) is the first listed.
NCT05073471 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05073471 about?
NCT05073471 is a clinical study titled "Music and Brain Stimulation for Upper Extremity Performance in Patients With Corticobasal Syndrome". This study is designed to investigate how musical patterns (e.g., patterned sensory enhancement, PSE) and non-invasive brain stimulation (e.g., transcranial direct current stimulation, tDCS) are effective to improve functional upper extremity performances in patients with corticobasal syndrome (CBS)...
What is the current status of trial NCT05073471?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2022-04-22. Estimated completion is 2026-06-30.
What conditions does trial NCT05073471 study?
This clinical trial studies the following conditions: Corticobasal Syndrome, Upper Extremity Dysfunction.
What interventions are being tested in trial NCT05073471?
The interventions under investigation include: Transcranial Direct Current Stimulation (tDCS) (DEVICE), Patterned Sensory Enhancement (PSE) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05073471?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05073471 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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