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NCT05063916 · ClinicalTrials.gov registry record · Phase 2

Phase II Study of AK104 (Cadonilimab) for Recurrent Small Cell Neuroendocrine Carcinomas of the Cervix

A Phase 2 study of Cervical Cancer and Cervix Cancer, sponsored by M.D. Anderson Cancer Center.

Active
Registry status
Phase 2
Development phase
18
Enrollment target
1
Study location

NCT05063916 is a Phase 2 study of Cervical Cancer and Cervix Cancer that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 18 participants, below the 570-participant average among 144 other Cervical Cancer trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05063916, a Phase 2 study of Cervical Cancer and Cervix Cancer, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
18 participants
Enrollment target
1
Study location

Study Summary

This is a Phase 2, single center, open-label, single-arm study designed to evaluate the efficacy, safety, tolerability, and immunogenicity of AK104 monotherapy in adult subjects with previously treated recurrent or metastatic high grade neuroendocrine cervical cancer.

Interventions

  • DRUG AK104

Study Locations (1)

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2022-02-28
Est. Completion 2027-08-01
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT05063916

The ClinicalTrials.gov registry entry for NCT05063916 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 570-participant average among 144 other Cervical Cancer trials with a reported enrollment target (97% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Cervical Cancer appearing as the primary indexed condition, and to 1 intervention - of which AK104 is the first listed.

NCT05063916 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05063916 about?

NCT05063916 is a clinical study titled "Phase II Study of AK104 (Cadonilimab) for Recurrent Small Cell Neuroendocrine Carcinomas of the Cervix". This is a Phase 2, single center, open-label, single-arm study designed to evaluate the efficacy, safety, tolerability, and immunogenicity of AK104 monotherapy in adult subjects with previously treated recurrent or metastatic high grade neuroendocrine cervical cancer.

What is the current status of trial NCT05063916?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2022-02-28. Estimated completion is 2027-08-01.

What conditions does trial NCT05063916 study?

This clinical trial studies the following conditions: Cervical Cancer, Cervix Cancer, Carcinomas.

What interventions are being tested in trial NCT05063916?

The interventions under investigation include: AK104 (DRUG).

Who is sponsoring clinical trial NCT05063916?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05063916 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.