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NCT05062629 · ClinicalTrials.gov registry record
United States Hypophosphatasia Molecular Research Center
A clinical trial of Hypophosphatasia, sponsored by Children's Mercy Hospital Kansas City.
- Recruiting
- Registry status
- 66
- Enrollment target
- 1
- Study location
NCT05062629 is a study of Hypophosphatasia that is actively recruiting participants, run by Children's Mercy Hospital Kansas City. The registered enrollment target is 66 participants, below the 73-participant average among 6 other Hypophosphatasia trials with a reported enrollment target (10% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05062629, a study of Hypophosphatasia, is actively recruiting participants, sponsored by Children's Mercy Hospital Kansas City.
- RECRUITING
- Registry status
- 66 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is being done to determine if cryptic alterations exist within or near to the ALPL gene in patients with a clinical diagnosis of hypophosphatasia, but without identifiable alteration on commercial testing. Additionally, the study aims to characterize functional effects of certain variants of uncertain significance in patients with clinical diagnosis of hypophosphatasia.
Conditions Studied
Interventions
- GENETIC Whole Genome Sequencing
Study Locations (1)
Missouri
- Children's Mercy Hospital - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2021-08-24 |
| Est. Completion | 2026-06-30 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05062629
The ClinicalTrials.gov registry entry for NCT05062629 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 66 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 73-participant average among 6 other Hypophosphatasia trials with a reported enrollment target (10% lower). The listed sponsor is Children's Mercy Hospital Kansas City, which has 184 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hypophosphatasia appearing as the primary indexed condition, and to 1 intervention - of which Whole Genome Sequencing is the first listed.
NCT05062629 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.
Frequently Asked Questions
What is clinical trial NCT05062629 about?
NCT05062629 is a clinical study titled "United States Hypophosphatasia Molecular Research Center". This study is being done to determine if cryptic alterations exist within or near to the ALPL gene in patients with a clinical diagnosis of hypophosphatasia, but without identifiable alteration on commercial testing. Additionally, the study aims to characterize functional effects of certain variants...
What is the current status of trial NCT05062629?
This trial is currently recruiting. The enrollment target is 66 participants. The study started on 2021-08-24. Estimated completion is 2026-06-30.
What conditions does trial NCT05062629 study?
This clinical trial studies the following conditions: Hypophosphatasia.
What interventions are being tested in trial NCT05062629?
The interventions under investigation include: Whole Genome Sequencing (GENETIC).
Who is sponsoring clinical trial NCT05062629?
This trial is sponsored by Children's Mercy Hospital Kansas City, which has 184 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05062629 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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-
Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)
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Read our methodology - how this data is sourced, computed, and verified.
Related
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