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NCT05054140 · ClinicalTrials.gov registry record · Phase 2
Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis
A Phase 2 study of Multiple Sclerosis, sponsored by Immunic.
- Active
- Registry status
- Phase 2
- Development phase
- 450
- Enrollment target
- 20
- Study locations
NCT05054140: Active Phase 2 study of Multiple Sclerosis, sponsored by Immunic.
NCT05054140 is a Phase 2 study of Multiple Sclerosis that is active but no longer recruiting, run by Immunic. The registered enrollment target is 450 participants, below the 584-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (23% lower). The trial reports 20 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05054140, a Phase 2 study of Multiple Sclerosis, is active but no longer recruiting, sponsored by Immunic.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 450 participants
- Enrollment target
- 20
- Study locations
Study Summary
Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients with Progressive Multiple Sclerosis - CALLIPER
Conditions Studied
Interventions
- DRUG IMU-838
- DRUG Placebo matching IMU-838
Study Locations (20)
Other
- MHAT Pulse - Blagoevgrad
- MHAT"Heart and Brain" EAD - Burgas
- Dr. Maya Danovska - Pleven
- Dr. Plamen Bozhinov - Pleven
- UMHAT Pulmed - Plovdiv
- Dr. Rositsa Krasteva - Rousse
- Dr. Nikolay Georgiev - Shumen
- MHAT Shumen - Shumen
- Dr. Ivan Milanov - Sofia
- MHAT Lyulin - Sofia
- Dr. Rosen Ikonomov - Sofia
- Dr. Penko Shotekov - Sofia
Florida
- Dr. Sonia Kalirao - Coral Springs
- Collier Neurologic Specialists - Naples
- Prof. James Scott - Ormond Beach
Georgia
- Shepherd Center - Atlanta
Illinois
- Consultants in Neurology, Ltd. - Northbrook
Maryland
- Dr. Daniel Becker - Lutherville
Michigan
- Dr. Mirela Cerghet - Detroit
New Mexico
- University of New Mexico (UNM), MS Specialty Clinic - Albuquerque
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 450 participants |
| Start Date | 2021-09-30 |
| Est. Completion | 2025-01-07 |
| Phase | Phase 2 |
What the registry record for NCT05054140 still lists
NCT05054140 is an interventional study that assigns participants to a tested intervention. The registered 450 participants enrollment target is mid-sized for trials with a published cap, below the 584-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (23% lower).
The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which IMU-838 is the first listed.
NCT05054140 names 20 study sites across 7 states, led by Other, Florida, Georgia.
Frequently Asked Questions
What is clinical trial NCT05054140 about?
NCT05054140 is a clinical study titled "Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis". Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients with Progressive Multiple Sclerosis - CALLIPER
What is the current status of trial NCT05054140?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 450 participants. The study started on 2021-09-30. Estimated completion is 2025-01-07.
What conditions does trial NCT05054140 study?
This clinical trial studies the following conditions: Multiple Sclerosis.
What interventions are being tested in trial NCT05054140?
The interventions under investigation include: IMU-838 (DRUG), Placebo matching IMU-838 (DRUG).
Who is sponsoring clinical trial NCT05054140?
This trial is sponsored by Immunic, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05054140 being conducted?
This trial has 20 study locations across Florida, Georgia, Illinois, Maryland, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05054140's enrollment target sits among peer trials
450 43rd of 315 higher than 273 of 315 other Multiple Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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