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NCT05053737 · ClinicalTrials.gov registry record · Phase 1

Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC

A Phase 1 study of Squamous Cell Carcinoma of Head and Neck, sponsored by University of Colorado, Denver.

Completed
Registry status
Phase 1
Development phase
11
Enrollment target
4
Study locations

NCT05053737 is a Phase 1 study of Squamous Cell Carcinoma of Head and Neck that has completed, run by University of Colorado, Denver. The registered enrollment target is 11 participants, below the 170-participant average among 37 other Squamous Cell Carcinoma of Head and Neck trials with a reported enrollment target (94% lower). The trial reports 4 study locations across 1 state.

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The verdict

NCT05053737, a Phase 1 study of Squamous Cell Carcinoma of Head and Neck, has completed, sponsored by University of Colorado, Denver.

COMPLETED
Registry status
Phase 1
Development phase
11 participants
Enrollment target
4
Study locations

Study Summary

To determine the outcomes of patients with specific head and neck cancer after undergoing radiation therapy with atezolizumab followed by surgery then radiation with or without chemotherapy according to national guidelines.

Interventions

  • DRUG Atezolizumab
  • RADIATION Stereotactic Body Radiation Therapy

Study Locations (4)

Colorado

  • Colorado Research Center - Aurora
  • Memorial Health Central - Colorado Springs
  • Memorial Hospital North - Colorado Springs
  • Highlands Ranch Hospital - Highlands Ranch

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2021-11-02
Est. Completion 2024-06-21
Phase Phase 1

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT05053737

The ClinicalTrials.gov registry entry for NCT05053737 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 170-participant average among 37 other Squamous Cell Carcinoma of Head and Neck trials with a reported enrollment target (94% lower). The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Squamous Cell Carcinoma of Head and Neck appearing as the primary indexed condition, and to 2 interventions - of which Atezolizumab is the first listed.

NCT05053737 reports 4 study locations spanning 1 distinct geographic area - top geographies include Colorado.

Frequently Asked Questions

What is clinical trial NCT05053737 about?

NCT05053737 is a clinical study titled "Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC". To determine the outcomes of patients with specific head and neck cancer after undergoing radiation therapy with atezolizumab followed by surgery then radiation with or without chemotherapy according to national guidelines.

What is the current status of trial NCT05053737?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2021-11-02. Estimated completion is 2024-06-21.

What conditions does trial NCT05053737 study?

This clinical trial studies the following conditions: Squamous Cell Carcinoma of Head and Neck.

What interventions are being tested in trial NCT05053737?

The interventions under investigation include: Atezolizumab (DRUG), Stereotactic Body Radiation Therapy (RADIATION).

Who is sponsoring clinical trial NCT05053737?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05053737 being conducted?

This trial has 4 study locations across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.