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NCT05048212 · ClinicalTrials.gov registry record · Phase 2

A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases

A Phase 2 study of Renal Cell Carcinoma and Brain Metastases, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
20
Enrollment target
1
Study location

NCT05048212: Recruiting Phase 2 study of Renal Cell Carcinoma and Brain Metastases, sponsored by M.D. Anderson Cancer Center.

NCT05048212 is a Phase 2 study of Renal Cell Carcinoma and Brain Metastases that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 20 participants, below the 243-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05048212, a Phase 2 study of Renal Cell Carcinoma and Brain Metastases, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

A Phase II Study of Nivolumab with Ipilimumab and Cabozantinib in Patients with Untreated Renal Cell Carcinoma Brain Metastases

Interventions

  • DRUG Nivolumab
  • DRUG Ipilimumab
  • DRUG Cabozantinib

Study Locations (1)

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2022-09-20
Est. Completion 2027-01-31
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

What NCT05048212 shows while recruiting

NCT05048212 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 243-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (92% lower).

The record links to 2 conditions, with Renal Cell Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Nivolumab is the first listed.

NCT05048212 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05048212 about?

NCT05048212 is a clinical study titled "A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases". A Phase II Study of Nivolumab with Ipilimumab and Cabozantinib in Patients with Untreated Renal Cell Carcinoma Brain Metastases

What is the current status of trial NCT05048212?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2022-09-20. Estimated completion is 2027-01-31.

What conditions does trial NCT05048212 study?

This clinical trial studies the following conditions: Renal Cell Carcinoma, Brain Metastases.

What interventions are being tested in trial NCT05048212?

The interventions under investigation include: Nivolumab (DRUG), Ipilimumab (DRUG), Cabozantinib (DRUG).

Who is sponsoring clinical trial NCT05048212?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05048212 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Renal Cell Carcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05048212's enrollment target sits among peer trials

20 109th of 121 higher than 10 of 121 other Renal Cell Carcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Renal Cell Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05048212, the US trial registry maintained by the National Library of Medicine. NCT05048212 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.