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NCT05033990 · ClinicalTrials.gov registry record

SPIROMICS Study of Early COPD Progression (SOURCE)

A clinical trial of COPD, Early-Onset, sponsored by University of Massachusetts, Worcester.

Recruiting
Registry status
1,000
Enrollment target
14
Study locations

NCT05033990 is a study of COPD, Early-Onset that is actively recruiting participants, run by University of Massachusetts, Worcester. The registered enrollment target is 1,000 participants. The trial reports 14 study locations across 12 states.

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The verdict

NCT05033990, a study of COPD, Early-Onset, is actively recruiting participants, sponsored by University of Massachusetts, Worcester.

RECRUITING
Registry status
1,000 participants
Enrollment target
14
Study locations

Study Summary

This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals. The study has three main goals: * To use CT scan imaging to identify which smokers will develop COPD. * To identify biomarkers predictive of smokers that will develop COPD. * To determine if sputum (phlegm) can be analyzed to predict which smokers will develop COPD. Procedures (methods): All participants will undergo study related questionnaires assessing medical history, smoke exposure and use, medication use, social and behavioral health, pulmonary symptoms, food frequency, and will provide nasal swab, blood, stool, and urine samples, pulmonary function testing to determine function, sputum induction to provide a sputum sample for airway biospecimen analysis, and CT imaging of the lungs.

Conditions Studied

Study Locations (14)

California

  • University of California Los Angeles - Los Angeles
  • University of California, San Francisco - San Francisco

New York

  • Columbia University - New York
  • Weill Cornell Medical Center - New York

Alabama

  • University of Alabama at Birmingham - Birmingham

Arizona

  • Mayo Clinic Arizona - Scottsdale

Colorado

  • National Jewish Health - Denver

Illinois

  • University of Illinois Chicago - Chicago

Iowa

  • University of Iowa - Iowa City

Maryland

  • Johns Hopkins Bayview Medical Center - Baltimore

Trial Details

FieldValue
Enrollment Target 1,000 participants
Start Date 2021-09-08
Est. Completion 2026-04

What the Registry Record Tells You About NCT05033990

The ClinicalTrials.gov registry entry for NCT05033990 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Massachusetts, Worcester, which has 240 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with COPD, Early-Onset appearing as the primary indexed condition, and to 0 interventions.

NCT05033990 reports 14 study locations spanning 12 distinct geographic areas - top geographies include California, New York, Alabama.

Frequently Asked Questions

What is clinical trial NCT05033990 about?

NCT05033990 is a clinical study titled "SPIROMICS Study of Early COPD Progression (SOURCE)". This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals. The study has three main goals: * To use CT scan imaging to identify which smokers will develop COPD. * To identify biomarkers pre...

What is the current status of trial NCT05033990?

This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2021-09-08. Estimated completion is 2026-04.

What conditions does trial NCT05033990 study?

This clinical trial studies the following conditions: COPD, Early-Onset.

Who is sponsoring clinical trial NCT05033990?

This trial is sponsored by University of Massachusetts, Worcester, which has 240 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05033990 being conducted?

This trial has 14 study locations across Alabama, Arizona, California, Colorado, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.