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Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
NCT05029726 · View on ClinicalTrials.gov ↗
Study Summary
Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids. Reducing the need for opiate analgesics in the post-operative setting has become a high priority in minimizing long-term opioid use in surgical patients. This study will serve to demonstrate the efficacy of the addition of regional analgesic techniques in reducing post-operative opioid requirements in patients undergoing common lumbar spinal surgical procedures.
Conditions Studied
Interventions
- DRUG Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine
- DRUG normal saline
Study Locations (1)
Illinois
- Rush University Medical Center — Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 125 participants |
| Start Date | 2022-02-01 |
| Est. Completion | 2027-04-30 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05029726
The ClinicalTrials.gov registry entry for NCT05029726 describes a study currently listed as recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 125 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is John O'Toole, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 10 conditions, with Degenerative Disc Disease appearing as the primary indexed condition, and to 2 interventions — of which Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05029726 reports 1 study location spanning 1 distinct geographic area — top geographies include Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05029726 about?
NCT05029726 is a clinical study titled "Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery". Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids. Reducing the need for opiate analgesics in the post-operative setting has become a high priority in minimizing long-term opioid use in surgical p...
What is the current status of trial NCT05029726?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 125 participants. The study started on 2022-02-01. Estimated completion is 2027-04-30.
What conditions does trial NCT05029726 study?
This clinical trial studies the following conditions: Degenerative Disc Disease, Lumbar Spinal Stenosis, Degenerative Spondylolisthesis, Lumbar Spondylosis, Lumbar Disc Herniation. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05029726?
The interventions under investigation include: Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine (DRUG), normal saline (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05029726?
This trial is sponsored by John O'Toole, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05029726 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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