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NCT05029726 · ClinicalTrials.gov registry record · Phase 4

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

A Phase 4 study of Degenerative Disc Disease and Lumbar Spinal Stenosis, sponsored by John O'Toole.

Recruiting
Registry status
Phase 4
Development phase
125
Enrollment target
1
Study location

NCT05029726 is a Phase 4 study of Degenerative Disc Disease and Lumbar Spinal Stenosis that is actively recruiting participants, run by John O'Toole. The registered enrollment target is 125 participants, below the 166-participant average among 42 other Degenerative Disc Disease trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05029726, a Phase 4 study of Degenerative Disc Disease and Lumbar Spinal Stenosis, is actively recruiting participants, sponsored by John O'Toole.

RECRUITING
Registry status
Phase 4
Development phase
125 participants
Enrollment target
1
Study location

Study Summary

Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids. Reducing the need for opiate analgesics in the post-operative setting has become a high priority in minimizing long-term opioid use in surgical patients. This study will serve to demonstrate the efficacy of the addition of regional analgesic techniques in reducing post-operative opioid requirements in patients undergoing common lumbar spinal surgical procedures.

Interventions

  • DRUG Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine
  • DRUG normal saline

Study Locations (1)

Illinois

  • Rush University Medical Center - Chicago

Trial Details

FieldValue
Enrollment Target 125 participants
Start Date 2022-02-01
Est. Completion 2027-04-30
Phase Phase 4

Sponsor

John O'Toole

1 total trials

What the Registry Record Tells You About NCT05029726

The ClinicalTrials.gov registry entry for NCT05029726 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 125 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 166-participant average among 42 other Degenerative Disc Disease trials with a reported enrollment target (25% lower). The listed sponsor is John O'Toole, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Degenerative Disc Disease appearing as the primary indexed condition, and to 2 interventions - of which Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine is the first listed.

NCT05029726 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT05029726 about?

NCT05029726 is a clinical study titled "Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery". Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids. Reducing the need for opiate analgesics in the post-operative setting has become a high priority in minimizing long-term opioid use in surgical p...

What is the current status of trial NCT05029726?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 125 participants. The study started on 2022-02-01. Estimated completion is 2027-04-30.

What conditions does trial NCT05029726 study?

This clinical trial studies the following conditions: Degenerative Disc Disease, Lumbar Spinal Stenosis, Degenerative Spondylolisthesis, Lumbar Spondylosis, Lumbar Disc Herniation.

What interventions are being tested in trial NCT05029726?

The interventions under investigation include: Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine (DRUG), normal saline (DRUG).

Who is sponsoring clinical trial NCT05029726?

This trial is sponsored by John O'Toole, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05029726 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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