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Lumbar Spinal Stenosis clinical trials
Every US clinical trial registered for Lumbar Spinal Stenosis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
19 US clinical trials · 9 currently recruiting
The research picture
Lumbar Spinal Stenosis has 19 registered US clinical trials, 9 of them open to new participants right now — about 47% of the total.
- 9
- recruiting participants now
- 47%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 2
- top sponsor: VA Office of Research and Development
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Stryker Instruments
NCT03072927
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
Columbia University
NCT06034405
Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression
Hospital for Special Surgery, New York
NCT05058287
Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman Device
Spinal Simplicity
NCT06355791
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
John O'Toole
NCT05029726
REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain
Pacific Research Institute
NCT05504499
Study Comparing Local/ MAC Anesthesia in Lumbar Decompression
Stanford University
NCT04992572
Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine
University of Colorado, Denver
NCT04066296
Lumbosacral Spinal Stenosis - Non-Invasive Postural Therapy for Older Adult Veterans
VA Office of Research and Development
NCT06089746
SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion
Lahey Clinic
NCT03570801
LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis
Empirical Spine
NCT03115983
A 5-year Superion™ IDS Clinical Outcomes Post-Approval Evaluation (SCOPE)
Boston Scientific Corporation
NCT04192591
Optimizing Impact of Manual Therapy on Lumbar Spinal Stenosis
University of Pittsburgh
NCT06023498
Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.
Primus Pharmaceuticals
NCT06157177
The STEPS - Totalis™ Trial
VertiFlex, Incorporated
NCT02079038
Post Epidural Steroid Injection Follow-up
Vanderbilt University Medical Center
NCT04207606
Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)
VA Office of Research and Development
NCT02697435
Vertos Mild - Post Market Patient Outcomes
The Center for Pain Relief
NCT01076244
Misoprostol for Spinal Stenosis
Dallas VA Medical Center
NCT04611464
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 1 |
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Lumbar Spinal Stenosis Trial Landscape
ClinicalTrials.gov lists 19 US studies indexed under Lumbar Spinal Stenosis, and 9 of those are currently open to recruitment — roughly 47% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Lumbar Spinal Stenosis shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Lumbar Spinal Stenosis is led by VA Office of Research and Development with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Lumbar Spinal Stenosis?
PlainTrial tracks 19 US clinical trials for Lumbar Spinal Stenosis, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Lumbar Spinal Stenosis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.