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ClinicalTrials.gov 9 recruiting now full pipeline small index

Lumbar Spinal Stenosis: full-pipeline trial registry

9 of 19 indexed Lumbar Spinal Stenosis trials are currently recruiting.

Corpus placement: #902 of 28,707 conditions by registered trial count.

19 US clinical trials · 9 currently recruiting · #902 of 28,707 conditions by registered trial count

Lumbar Spinal Stenosis: 19 US clinical trials tracked, 9 recruiting.

Lumbar Spinal Stenosis is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 2 of these trials.

Enrollment posture brief

Registry condition lumbar-spinal-stenosis

OPEN 9 | RECR 47% | LATE 3 | EARLY 2 | RANK #902 | SPON 2

Nearest open-share peer: Breast Cancer Stage I (47% recruiting · 19 trials)

Amyotrophic Lateral Sclerosi52.6%Lumbar Spinal Stenosis (this)47%Anesthesia, Local42.1%Alcohol Consumption36.8%Attention Deficit Hyperactiv26.3%
Open-enrollment share among volume-matched conditions near Lumbar Spinal Stenosis

Lumbar Spinal Stenosis lists 9 open slots (47% of 19 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Lumbar Spinal Stenosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Lumbar Spinal Stenosis recruits in line with its size-band peers.

    9 of 19 indexed trials (47.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Lumbar Spinal Stenosis trials is spread across many organizations.

    VA Office of Research and Development accounts for 2 of 19 trials (10.5%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Typical Lumbar Spinal Stenosis enrolment sits around 100 participants.

    Median target enrolment is 100 among the 19 trials that report a genuine target (sentinel values excluded). 6 of those (31.6%) plan for fewer than 100 participants.

  4. Lumbar Spinal Stenosis research is mostly interventional.

    15 interventional and 4 observational studies make up this index (78.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21Phase 31Phase 42

Open and recent trials

19 total, page 1 of 1

RECRUITING 8,000 participants

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

Stryker Instruments

NCT03072927

RECRUITING 1,663 participants

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Columbia University

NCT06034405

RECRUITING Phase 3 150 participants

Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

Hospital for Special Surgery, New York

NCT05058287

RECRUITING NA 150 participants

Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman Device

Spinal Simplicity

NCT06355791

RECRUITING Phase 4 125 participants

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

John O'Toole

NCT05029726

RECRUITING NA 100 participants

REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain

Pacific Research Institute

NCT05504499

RECRUITING Early Phase 1 100 participants

Study Comparing Local/ MAC Anesthesia in Lumbar Decompression

Stanford University

NCT04992572

RECRUITING Phase 2 100 participants

Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine

University of Colorado, Denver

NCT04066296

RECRUITING NA 20 participants

Lumbosacral Spinal Stenosis - Non-Invasive Postural Therapy for Older Adult Veterans

VA Office of Research and Development

NCT06089746

ACTIVE NOT RECRUITING NA 662 participants

SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion

Lahey Clinic

NCT03570801

ACTIVE NOT RECRUITING NA 299 participants

LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis

Empirical Spine

NCT03115983

ACTIVE NOT RECRUITING NA 166 participants

A 5-year Superion™ IDS Clinical Outcomes Post-Approval Evaluation (SCOPE)

Boston Scientific Corporation

NCT04192591

ACTIVE NOT RECRUITING NA 60 participants

Optimizing Impact of Manual Therapy on Lumbar Spinal Stenosis

University of Pittsburgh

NCT06023498

ACTIVE NOT RECRUITING Phase 4 50 participants

Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.

Primus Pharmaceuticals

NCT06157177

COMPLETED NA 180 participants

The STEPS - Totalis™ Trial

VertiFlex, Incorporated

NCT02079038

COMPLETED 100 participants

Post Epidural Steroid Injection Follow-up

Vanderbilt University Medical Center

NCT04207606

COMPLETED NA 55 participants

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

VA Office of Research and Development

NCT02697435

COMPLETED NA 46 participants

Vertos Mild - Post Market Patient Outcomes

The Center for Pain Relief

NCT01076244

COMPLETED 23 participants

Misoprostol for Spinal Stenosis

Dallas VA Medical Center

NCT04611464

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 1
Phase 4 2

Named interventions

Most-linked intervention names on Lumbar Spinal Stenosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Comparator Surgical Procedure Procedure
1 trials
Totalis Device
1 trials
Imaging-Directed Care Other
1 trials
Patient-Centered Care Other
1 trials
Minimally Invasive Lumbar Decompression Procedure
1 trials
Post Epidural Steroid Injection Follow-up Behavioral
1 trials
Metaxalone 640 mg Oral Tablet Drug
1 trials
Intramuscular Electroacupuncture Other
1 trials

US sites by state

Facility locations filed on Lumbar Spinal Stenosis trials. A trial with sites in several states counts in each.

California 8 trials
Florida 7 trials
Pennsylvania 5 trials
Massachusetts 5 trials
Georgia 5 trials
Texas 4 trials
Ohio 4 trials
New York 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Lumbar Spinal Stenosis page

19 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Lumbar Spinal Stenosis condition card totals 19 registered trials; most-linked intervention Comparator Surgical Procedure; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.