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ClinicalTrials.gov 9 recruiting now official registry

Lumbar Spinal Stenosis clinical trials

Every US clinical trial registered for Lumbar Spinal Stenosis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

19 US clinical trials · 9 currently recruiting

The research picture

Lumbar Spinal Stenosis has 19 registered US clinical trials, 9 of them open to new participants right now — about 47% of the total.

9
recruiting participants now
47%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: VA Office of Research and Development

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 8,000 participants

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

Stryker Instruments

NCT03072927

RECRUITING 1,663 participants

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Columbia University

NCT06034405

RECRUITING Phase 3 150 participants

Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

Hospital for Special Surgery, New York

NCT05058287

RECRUITING NA 150 participants

Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman Device

Spinal Simplicity

NCT06355791

RECRUITING Phase 4 125 participants

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

John O'Toole

NCT05029726

RECRUITING NA 100 participants

REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain

Pacific Research Institute

NCT05504499

RECRUITING Early Phase 1 100 participants

Study Comparing Local/ MAC Anesthesia in Lumbar Decompression

Stanford University

NCT04992572

RECRUITING Phase 2 100 participants

Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine

University of Colorado, Denver

NCT04066296

RECRUITING NA 20 participants

Lumbosacral Spinal Stenosis - Non-Invasive Postural Therapy for Older Adult Veterans

VA Office of Research and Development

NCT06089746

ACTIVE NOT RECRUITING NA 662 participants

SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion

Lahey Clinic

NCT03570801

ACTIVE NOT RECRUITING NA 299 participants

LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis

Empirical Spine

NCT03115983

ACTIVE NOT RECRUITING NA 166 participants

A 5-year Superion™ IDS Clinical Outcomes Post-Approval Evaluation (SCOPE)

Boston Scientific Corporation

NCT04192591

ACTIVE NOT RECRUITING NA 60 participants

Optimizing Impact of Manual Therapy on Lumbar Spinal Stenosis

University of Pittsburgh

NCT06023498

ACTIVE NOT RECRUITING Phase 4 50 participants

Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.

Primus Pharmaceuticals

NCT06157177

COMPLETED NA 180 participants

The STEPS - Totalis™ Trial

VertiFlex, Incorporated

NCT02079038

COMPLETED 100 participants

Post Epidural Steroid Injection Follow-up

Vanderbilt University Medical Center

NCT04207606

COMPLETED NA 55 participants

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

VA Office of Research and Development

NCT02697435

COMPLETED NA 46 participants

Vertos Mild - Post Market Patient Outcomes

The Center for Pain Relief

NCT01076244

COMPLETED 23 participants

Misoprostol for Spinal Stenosis

Dallas VA Medical Center

NCT04611464

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 1
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Lumbar Spinal Stenosis Trial Landscape

ClinicalTrials.gov lists 19 US studies indexed under Lumbar Spinal Stenosis, and 9 of those are currently open to recruitment — roughly 47% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Lumbar Spinal Stenosis shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Lumbar Spinal Stenosis is led by VA Office of Research and Development with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Lumbar Spinal Stenosis?

PlainTrial tracks 19 US clinical trials for Lumbar Spinal Stenosis, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lumbar Spinal Stenosis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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