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NCT06462729 · ClinicalTrials.gov registry record · Phase 1
LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF)
A Phase 1 study of Degenerative Disc Disease and Lumbar Spine Degeneration, sponsored by Locate Bio Pty.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
- 3
- Study locations
NCT06462729: Recruiting Phase 1 study of Degenerative Disc Disease and Lumbar Spine Degeneration, sponsored by Locate Bio Pty.
NCT06462729 is a Phase 1 study of Degenerative Disc Disease and Lumbar Spine Degeneration that is actively recruiting participants, run by Locate Bio Pty. The registered enrollment target is 40 participants, below the 168-participant average among 42 other Degenerative Disc Disease trials with a reported enrollment target (76% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06462729, a Phase 1 study of Degenerative Disc Disease and Lumbar Spine Degeneration, is actively recruiting participants, sponsored by Locate Bio Pty.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
- 3
- Study locations
Study Summary
The objective of this study is to evaluate the safety and effectiveness of LDGraft (investigational device) compared to 100% human tissue product allograft bone (control) when applied in an ALIF procedure in the treatment of patients with lumbar degenerative disc disease (DDD).
Primary Outcome
Radiographic fusion defined as evidence of bridging bone by CT scan
Conditions Studied
Interventions
- DEVICE LDGraft
- OTHER Allograft Bone
Study Locations (3)
New South Wales
- Newcastle Private Hospital - Newcastle
- Macquarie University - Sydney
Indiana
- Orthopaedics NorthEast - Fort Wayne
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2024-11-12 |
| Est. Completion | 2027-12 |
| Phase | Phase 1 |
What NCT06462729 shows while recruiting
NCT06462729 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 168-participant average among 42 other Degenerative Disc Disease trials with a reported enrollment target (76% lower).
The record links to 4 conditions, with Degenerative Disc Disease appearing as the primary indexed condition, and to 2 interventions - of which LDGraft is the first listed.
NCT06462729 reports a single indexed study location in New South Wales, Indiana.
Frequently Asked Questions
What is clinical trial NCT06462729 about?
NCT06462729 is a clinical study titled "LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF)". The objective of this study is to evaluate the safety and effectiveness of LDGraft (investigational device) compared to 100% human tissue product allograft bone (control) when applied in an ALIF procedure in the treatment of patients with lumbar degenerative disc disease (DDD).
What is the current status of trial NCT06462729?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2024-11-12. Estimated completion is 2027-12.
What conditions does trial NCT06462729 study?
This clinical trial studies the following conditions: Degenerative Disc Disease, Lumbar Spine Degeneration, Spine Disease, Lumbar Disc Disease.
What interventions are being tested in trial NCT06462729?
The interventions under investigation include: LDGraft (DEVICE), Allograft Bone (OTHER).
Who is sponsoring clinical trial NCT06462729?
This trial is sponsored by Locate Bio Pty, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06462729 being conducted?
This trial has 3 study locations across Indiana, New South Wales. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Degenerative Disc Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06462729's enrollment target sits among peer trials
40 33rd of 42 higher than 9 of 42 other Degenerative Disc Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Degenerative Disc Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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