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NCT04982926 · ClinicalTrials.gov registry record · Phase 1
A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor Cancer
A Phase 1 study, sponsored by Taiho Oncology.
- Terminated
- Registry status
- Phase 1
- Development phase
- 29
- Enrollment target
NCT04982926: Clinical Trial Phase 1 study, sponsored by Taiho Oncology.
NCT04982926 is a Phase 1 study that was terminated before completion, run by Taiho Oncology. The registered enrollment target is 29 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (52% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04982926, a Phase 1 study, was terminated before completion, sponsored by Taiho Oncology.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 29 participants
- Enrollment target
Study Summary
This is a first-in-human, open label, multicenter study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and the preliminary antitumor activity of TAS2940 in patients with advanced or metastatic solid tumors who are not candidates for approved or available therapies.
Primary Outcome
Determine the incidence of dose-liming toxicities (DLTs) and adverse events (AEs) graded according to National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) v5.0 within the first cycle
Interventions
- DRUG TAS2940
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2021-09-16 |
| Est. Completion | 2025-03-24 |
| Phase | Phase 1 |
Why NCT04982926 stopped before completion
NCT04982926 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (52% lower).
The record links to 0 conditions, and to 1 intervention - of which TAS2940 is the first listed.
NCT04982926 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04982926 about?
NCT04982926 is a clinical study titled "A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor Cancer". This is a first-in-human, open label, multicenter study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and the preliminary antitumor activity of TAS2940 in patients with advanced or metastatic solid tumors who are not candidates for approved or available therapies.
What is the current status of trial NCT04982926?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 29 participants. The study started on 2021-09-16. Estimated completion is 2025-03-24.
What interventions are being tested in trial NCT04982926?
The interventions under investigation include: TAS2940 (DRUG).
Who is sponsoring clinical trial NCT04982926?
This trial is sponsored by Taiho Oncology, which has 52 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04982926's enrollment target sits among peer trials
29 1440th of 2000 higher than 554 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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