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ACTIVE NOT RECRUITING Phase 3

SARC041: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma

NCT04967521 · View on ClinicalTrials.gov ↗

Study Summary

This is a Phase 3 randomized double-blind study of abemaciclib versus placebo. Patients with progression of disease will cross over to open label abemaciclib.

Interventions

  • DRUG Placebo
  • DRUG Abemaciclib

Study Locations (9)

Colorado

  • University of Colorado Cancer Center, Anschutz Medical Campus — Aurora

Florida

  • Mayo Clinic Florida — Jacksonville

Illinois

  • Northwestern University — Chicago

Massachusetts

  • Massachusetts General Hospital Cancer Center — Boston

Missouri

  • Washington University School of Medicine — St Louis

New York

  • Memorial Sloan Kettering Cancer Center — New York

North Carolina

  • Duke University — Durham

Oregon

  • Oregon Health & Science University — Portland

Trial Details

FieldValue
Enrollment Target 108 participants
Start Date 2021-11-11
Est. Completion 2026-12
Phase Phase 3

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04967521

The ClinicalTrials.gov registry entry for NCT04967521 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 108 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sarcoma Alliance for Research through Collaboration, which has 37 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Advanced Dedifferentiated Liposarcoma appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04967521 reports 9 study locations spanning 9 distinct geographic areas — top geographies include Colorado, Florida, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04967521 about?

NCT04967521 is a clinical study titled "SARC041: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma". This is a Phase 3 randomized double-blind study of abemaciclib versus placebo. Patients with progression of disease will cross over to open label abemaciclib.

What is the current status of trial NCT04967521?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 108 participants. The study started on 2021-11-11. Estimated completion is 2026-12.

What conditions does trial NCT04967521 study?

This clinical trial studies the following conditions: Advanced Dedifferentiated Liposarcoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04967521?

The interventions under investigation include: Placebo (DRUG), Abemaciclib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04967521?

This trial is sponsored by Sarcoma Alliance for Research through Collaboration, which has 37 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04967521 being conducted?

This trial has 9 study locations across Colorado, Florida, Illinois, Massachusetts, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial