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NCT04956861 · ClinicalTrials.gov registry record · NA

HIV-1, Insufficient Sleep and Vascular Endothelial Dysfunction

A NA study, sponsored by University of Colorado, Boulder.

Completed
Registry status
NA
Development phase
88
Enrollment target

NCT04956861 is a NA study that has completed, run by University of Colorado, Boulder. The registered enrollment target is 88 participants.

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The verdict

NCT04956861, a NA study, has completed, sponsored by University of Colorado, Boulder.

COMPLETED
Registry status
NA
Development phase
88 participants
Enrollment target

Study Summary

The investigators hypothesize that chronic insufficient sleep is associated with diminished endothelium-dependent nitric oxide-mediated vasodilation and tissue-type plasminogen activator release in anti-retroviral (ART)-treated HIV-1-seropositive adults. Furthermore, the investigators hypothesize that the postulated diminishment in endothelial vasodilator and fibrinolytic function with insufficient sleep will be due, at least in part, to increased oxidative stress. Moreover, increasing sleep duration and improving sleep quality will increase both endothelium-dependent nitric oxide-mediated vasodilation and endothelial tissue-type plasminogen activator release in ART-treated HIV-1-seropositive adults. Increases in endothelial vasodilator and fibrinolytic function will be due, at least in part, to reduced oxidative stress.

Interventions

  • BEHAVIORAL Individualized Targeted Sleep

Trial Details

FieldValue
Enrollment Target 88 participants
Start Date 2015-12-17
Est. Completion 2020-08-07
Phase NA

Sponsor

University of Colorado, Boulder

69 total trials

What the Registry Record Tells You About NCT04956861

The ClinicalTrials.gov registry entry for NCT04956861 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Colorado, Boulder, which has 69 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Individualized Targeted Sleep is the first listed.

NCT04956861 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04956861 about?

NCT04956861 is a clinical study titled "HIV-1, Insufficient Sleep and Vascular Endothelial Dysfunction". The investigators hypothesize that chronic insufficient sleep is associated with diminished endothelium-dependent nitric oxide-mediated vasodilation and tissue-type plasminogen activator release in anti-retroviral (ART)-treated HIV-1-seropositive adults. Furthermore, the investigators hypothesize th...

What is the current status of trial NCT04956861?

This trial is currently completed. It is a NA study. The enrollment target is 88 participants. The study started on 2015-12-17. Estimated completion is 2020-08-07.

What interventions are being tested in trial NCT04956861?

The interventions under investigation include: Individualized Targeted Sleep (BEHAVIORAL).

Who is sponsoring clinical trial NCT04956861?

This trial is sponsored by University of Colorado, Boulder, which has 69 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.