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NCT04920864 · ClinicalTrials.gov registry record · NA

rTMS, Stress and Opioid Use Disorder

A NA study of Opioid Use Disorder, sponsored by Wayne State University.

Active
Registry status
NA
Development phase
32
Enrollment target
1
Study location

NCT04920864 is a NA study of Opioid Use Disorder that is active but no longer recruiting, run by Wayne State University. The registered enrollment target is 32 participants, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04920864, a NA study of Opioid Use Disorder, is active but no longer recruiting, sponsored by Wayne State University.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
32 participants
Enrollment target
1
Study location

Study Summary

Opioid agonist treatments are the gold standard for treating opioid use disorder (OUD). Yet, even effective treatments average only 50% six-month retention. Despite extensive research into treatment options, it remains important to improve understanding of factors that contribute to relapse and identify interventions to mitigate these risks. Stress-exposure is problematic for people trying to recover from substance use disorders (SUDs) because it weakens inhibition of automatic behaviors and increases drug craving and likelihood of relapse. However, paths through which stress affects behavior are incompletely understood and current SUD treatments do not target effects of stress on drug use. This project will explore whether repetitive transcranial magnetic stimulation (rTMS) might improve treatment outcomes for people with OUD entering methadone treatment. The investigators will examine the impact of rTMS treatment over one of two theoretically-driven neural targets on substance use and cognitive outcomes associated with treatment success (executive function and emotional arousal).

Conditions Studied

Interventions

  • DEVICE rTMS

Study Locations (1)

Michigan

  • Tolan Park Medical Building - Detroit

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2022-04-01
Est. Completion 2026-12
Phase NA

Sponsor

Wayne State University

163 total trials

What the Registry Record Tells You About NCT04920864

The ClinicalTrials.gov registry entry for NCT04920864 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (99% lower). The listed sponsor is Wayne State University, which has 163 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Opioid Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which rTMS is the first listed.

NCT04920864 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT04920864 about?

NCT04920864 is a clinical study titled "rTMS, Stress and Opioid Use Disorder". Opioid agonist treatments are the gold standard for treating opioid use disorder (OUD). Yet, even effective treatments average only 50% six-month retention. Despite extensive research into treatment options, it remains important to improve understanding of factors that contribute to relapse and iden...

What is the current status of trial NCT04920864?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 32 participants. The study started on 2022-04-01. Estimated completion is 2026-12.

What conditions does trial NCT04920864 study?

This clinical trial studies the following conditions: Opioid Use Disorder.

What interventions are being tested in trial NCT04920864?

The interventions under investigation include: rTMS (DEVICE).

Who is sponsoring clinical trial NCT04920864?

This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04920864 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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