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NCT04919811 · ClinicalTrials.gov registry record · Phase 2
Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC
A Phase 2 study of Non-Small Cell Lung Cancer, sponsored by Nuvation Bio.
- Active
- Registry status
- Phase 2
- Development phase
- 217
- Enrollment target
- 20
- Study locations
NCT04919811: Active Phase 2 study of Non-Small Cell Lung Cancer, sponsored by Nuvation Bio.
NCT04919811 is a Phase 2 study of Non-Small Cell Lung Cancer that is active but no longer recruiting, run by Nuvation Bio. The registered enrollment target is 217 participants, below the 652-participant average among 454 other Non-Small Cell Lung Cancer trials with a reported enrollment target (67% lower). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04919811, a Phase 2 study of Non-Small Cell Lung Cancer, is active but no longer recruiting, sponsored by Nuvation Bio.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 217 participants
- Enrollment target
- 20
- Study locations
Study Summary
The main purpose of the study is to evaluate safety and efficacy of taletrectinib (also known as AB-106 or DS-6051b) monotherapy in the treatment of advanced NSCLC.
Primary Outcome
Confirmed ORR according to Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 assessed by an independent radiology review committee (IRC)
Conditions Studied
Interventions
- DRUG Taletrectinib
Study Locations (20)
California
- Beverly Hills Cancer Center - Beverly Hills
- The Oncology Institute of Hope and Innovation - Glendale
- Moores Cancer Center at UC San Diego - La Jolla
- Keck Medicine of University of Southern California - Los Angeles
- UCI Medical Center - Orange
- Ventura County Hematology-Oncology Specialists - Oxnard
Florida
- SCRI - Florida Cancer Specialists South - Fort Meyers
- Memorial Cancer Institute at Memorial Hospital East - Hollywood
- Cancer Specialists of North Florida - Jacksonville
- Memorial Cancer Institute at Memorial Hospital West - Pembroke Pines
Texas
- Texas Oncology, P.A. - Dallas
- Renovatio Clinical - El Paso
- MD Anderson Cancer Center - Houston
- Renovatio Clinical - The Woodlands
Louisiana
- SCRI - Hematology Oncology Clinic - Baton Rouge
Minnesota
- Mayo Clinic - Rochester
New Jersey
- Center for Cancer Research - Brick
Ohio
- Cleveland Clinic Foundation - Cleveland
Tennessee
- SCRI - Tennessee Oncology - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 217 participants |
| Start Date | 2021-09-01 |
| Est. Completion | 2027-12 |
| Phase | Phase 2 |
What the registry record for NCT04919811 still lists
NCT04919811 is an interventional study that assigns participants to a tested intervention. The registered 217 participants enrollment target is mid-sized for trials with a published cap, below the 652-participant average among 454 other Non-Small Cell Lung Cancer trials with a reported enrollment target (67% lower).
The record links to 1 condition, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 1 intervention - of which Taletrectinib is the first listed.
NCT04919811 names 20 study sites across 9 states, led by California, Florida, Texas.
Frequently Asked Questions
What is clinical trial NCT04919811 about?
NCT04919811 is a clinical study titled "Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC". The main purpose of the study is to evaluate safety and efficacy of taletrectinib (also known as AB-106 or DS-6051b) monotherapy in the treatment of advanced NSCLC.
What is the current status of trial NCT04919811?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 217 participants. The study started on 2021-09-01. Estimated completion is 2027-12.
What conditions does trial NCT04919811 study?
This clinical trial studies the following conditions: Non-Small Cell Lung Cancer.
What interventions are being tested in trial NCT04919811?
The interventions under investigation include: Taletrectinib (DRUG).
Who is sponsoring clinical trial NCT04919811?
This trial is sponsored by Nuvation Bio, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04919811 being conducted?
This trial has 20 study locations across California, Florida, Louisiana, Minnesota, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04919811's enrollment target sits among peer trials
217 158th of 454 higher than 297 of 454 other Non-Small Cell Lung Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Non-Small Cell Lung Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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