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NCT04919317 · ClinicalTrials.gov registry record · Phase 2
Combination Dexamethasone and Bupivacaine Pain Control in Reduction Mammaplasty
A Phase 2 study of Pain, Postoperative and Mammaplasty, sponsored by Temple University.
- Completed
- Registry status
- Phase 2
- Development phase
- 56
- Enrollment target
- 1
- Study location
NCT04919317: Completed Phase 2 study of Pain, Postoperative and Mammaplasty, sponsored by Temple University.
NCT04919317 is a Phase 2 study of Pain, Postoperative and Mammaplasty that has completed, run by Temple University. The registered enrollment target is 56 participants, below the 273-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04919317, a Phase 2 study of Pain, Postoperative and Mammaplasty, has completed, sponsored by Temple University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 56 participants
- Enrollment target
- 1
- Study location
Study Summary
The addition of dexamethasone to non-liposomal bupivacaine in perineural blocks has been shown to enhance pain control and prolong the time until first request for postoperative narcotics in the fields of orthopedic, thoracic, and gynecologic surgery. This has not been investigated in any types of breast surgery. The investigators assessed if the combination of dexamethasone to bupivacaine in the preoperative field block prior to bilateral breast reduction surgery resulted in improved pain control relative to bupivacaine alone.
Primary Outcome
Patient-reported pain scores on a scale of 1-10 (1 is low or no pain and 10 is the highest amount of pain)
Conditions Studied
Interventions
- DRUG Saline
- DRUG Dexamethasone 4mg
Study Locations (1)
Pennsylvania
- Temple University Hospital - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2017-09-29 |
| Est. Completion | 2020-11-25 |
| Phase | Phase 2 |
What the finished NCT04919317 record still lists
NCT04919317 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 273-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (79% lower).
The record links to 2 conditions, with Pain, Postoperative appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.
NCT04919317 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04919317 about?
NCT04919317 is a clinical study titled "Combination Dexamethasone and Bupivacaine Pain Control in Reduction Mammaplasty". The addition of dexamethasone to non-liposomal bupivacaine in perineural blocks has been shown to enhance pain control and prolong the time until first request for postoperative narcotics in the fields of orthopedic, thoracic, and gynecologic surgery. This has not been investigated in any types of b...
What is the current status of trial NCT04919317?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 56 participants. The study started on 2017-09-29. Estimated completion is 2020-11-25.
What conditions does trial NCT04919317 study?
This clinical trial studies the following conditions: Pain, Postoperative, Mammaplasty.
What interventions are being tested in trial NCT04919317?
The interventions under investigation include: Saline (DRUG), Dexamethasone 4mg (DRUG).
Who is sponsoring clinical trial NCT04919317?
This trial is sponsored by Temple University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04919317 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain, Postoperative
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04919317's enrollment target sits among peer trials
56 86th of 113 higher than 27 of 113 other Pain, Postoperative trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Postoperative trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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