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NCT04919317 · ClinicalTrials.gov registry record · Phase 2

Combination Dexamethasone and Bupivacaine Pain Control in Reduction Mammaplasty

A Phase 2 study of Pain, Postoperative and Mammaplasty, sponsored by Temple University.

Completed
Registry status
Phase 2
Development phase
56
Enrollment target
1
Study location

NCT04919317 is a Phase 2 study of Pain, Postoperative and Mammaplasty that has completed, run by Temple University. The registered enrollment target is 56 participants, below the 272-participant average among 108 other Pain, Postoperative trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04919317, a Phase 2 study of Pain, Postoperative and Mammaplasty, has completed, sponsored by Temple University.

COMPLETED
Registry status
Phase 2
Development phase
56 participants
Enrollment target
1
Study location

Study Summary

The addition of dexamethasone to non-liposomal bupivacaine in perineural blocks has been shown to enhance pain control and prolong the time until first request for postoperative narcotics in the fields of orthopedic, thoracic, and gynecologic surgery. This has not been investigated in any types of breast surgery. The investigators assessed if the combination of dexamethasone to bupivacaine in the preoperative field block prior to bilateral breast reduction surgery resulted in improved pain control relative to bupivacaine alone.

Interventions

  • DRUG Saline
  • DRUG Dexamethasone 4mg

Study Locations (1)

Pennsylvania

  • Temple University Hospital - Philadelphia

Trial Details

FieldValue
Enrollment Target 56 participants
Start Date 2017-09-29
Est. Completion 2020-11-25
Phase Phase 2

Sponsor

Temple University

163 total trials

What the Registry Record Tells You About NCT04919317

The ClinicalTrials.gov registry entry for NCT04919317 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 272-participant average among 108 other Pain, Postoperative trials with a reported enrollment target (79% lower). The listed sponsor is Temple University, which has 163 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Pain, Postoperative appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.

NCT04919317 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT04919317 about?

NCT04919317 is a clinical study titled "Combination Dexamethasone and Bupivacaine Pain Control in Reduction Mammaplasty". The addition of dexamethasone to non-liposomal bupivacaine in perineural blocks has been shown to enhance pain control and prolong the time until first request for postoperative narcotics in the fields of orthopedic, thoracic, and gynecologic surgery. This has not been investigated in any types of b...

What is the current status of trial NCT04919317?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 56 participants. The study started on 2017-09-29. Estimated completion is 2020-11-25.

What conditions does trial NCT04919317 study?

This clinical trial studies the following conditions: Pain, Postoperative, Mammaplasty.

What interventions are being tested in trial NCT04919317?

The interventions under investigation include: Saline (DRUG), Dexamethasone 4mg (DRUG).

Who is sponsoring clinical trial NCT04919317?

This trial is sponsored by Temple University, which has 163 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04919317 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.