Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING

ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)

NCT04883905 · View on ClinicalTrials.gov ↗

Study Summary

This global patient registry is being conducted to characterize the natural history and real-world clinical management of patients with AHP, and to further characterize the real-world safety and effectiveness of givosiran and other approved AHP therapies.

Conditions Studied

Study Locations (20)

Other

  • Clinical Trial Site — Brussels
  • Clinical Trial Site — Leuven
  • Clinical Trial Site — Bordeaux
  • Clinical Trial Site — Paris
  • Clinical Trial Site — Toulouse
  • Clinical Trial Site — Berlin
  • Clinical Trial Site — Chemnitz

Alabama

  • Clinical Trial Site — Birmingham

Arizona

  • Clinical Trial Site — Gilbert

California

  • Clinical Trial Site — San Francisco

Maryland

  • Clinical Trial Site — Baltimore

Massachusetts

  • Clinical Trial Site — Boston

Minnesota

  • Clinical Trial Site — Minneapolis

New York

  • Clinical Trial Site — New York

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2021-04-26
Est. Completion 2027-04-01

Sponsor

Alnylam Pharmaceuticals

81 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04883905

The ClinicalTrials.gov registry entry for NCT04883905 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alnylam Pharmaceuticals, which has 81 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Acute Hepatic Porphyria appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04883905 reports 20 study locations spanning 14 distinct geographic areas — top geographies include Other, Alabama, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04883905 about?

NCT04883905 is a clinical study titled "ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)". This global patient registry is being conducted to characterize the natural history and real-world clinical management of patients with AHP, and to further characterize the real-world safety and effectiveness of givosiran and other approved AHP therapies.

What is the current status of trial NCT04883905?

This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2021-04-26. Estimated completion is 2027-04-01.

What conditions does trial NCT04883905 study?

This clinical trial studies the following conditions: Acute Hepatic Porphyria. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

Who is sponsoring clinical trial NCT04883905?

This trial is sponsored by Alnylam Pharmaceuticals, which has 81 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04883905 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Maryland, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial