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NCT04871451 · ClinicalTrials.gov registry record · Phase 2
Extension Study of ABP-19000 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 in Cervical Dystonia
A Phase 2 study of Cervical Dystonia, sponsored by AEON Biopharma.
- Completed
- Registry status
- Phase 2
- Development phase
- 51
- Enrollment target
- 20
- Study locations
NCT04871451: Completed Phase 2 study of Cervical Dystonia, sponsored by AEON Biopharma.
NCT04871451 is a Phase 2 study of Cervical Dystonia that has completed, run by AEON Biopharma. The registered enrollment target is 51 participants, below the 84-participant average among 15 other Cervical Dystonia trials with a reported enrollment target (39% lower). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04871451, a Phase 2 study of Cervical Dystonia, has completed, sponsored by AEON Biopharma.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 51 participants
- Enrollment target
- 20
- Study locations
Study Summary
This Open-label Extension trial will evaluate the safety and efficacy of ABP-450 for the treatment of cervical dystonia in adults. The study will enroll 60 patients across approximately 42 sites in the United States from Phase 2 (ABP-19000) trial. Study subjects who had their initial dose of study drug in the Phase 2 trial, irrespective of treatment allocation, will be eligible to enroll in this OLE study.
Primary Outcome
The primary safety endpoint will be the incidence of treatment-related serious adverse events since the start of treatment by Treatment Group when dosed with ABP-450 between Low Dose and High Dose.
Conditions Studied
Interventions
- DRUG ABP-450
Study Locations (20)
Florida
- Infinity Clinical Research LLC - Hollywood
- Brainstorm Research - Miami
- University of South Florida - Tampa
- Neurology One - Winter Park
California
- Parkinson's and Movement Disorder Institute - Fountain Valley
- Neuro Pain Medical Center - Fresno
- Loma Linda University - Loma Linda
Ohio
- The Cleveland Clinic Foundation - Cleveland
- Cleveland Clinic Lou Ruvo Center for Brain Health - Cleveland
- The Orthopedic Foundation - New Albany
Michigan
- Michigan State University - East Lansing
- Quest Research Institute - Hunt - PPDS - Farmington Hills
Tennessee
- Veracity Neuroscience LLC - Memphis
- Vanderbilt University Medical Center - Nashville
Arizona
- Arizona Neuroscience Research - Phoenix
Connecticut
- New England Institute for Neurology and Headache - Stamford
Georgia
- Emory University - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 51 participants |
| Start Date | 2021-07-27 |
| Est. Completion | 2023-07-24 |
| Phase | Phase 2 |
What the finished NCT04871451 record still lists
NCT04871451 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 51 participants, a relatively small participant target, below the 84-participant average among 15 other Cervical Dystonia trials with a reported enrollment target (39% lower).
The record links to 1 condition, with Cervical Dystonia appearing as the primary indexed condition, and to 1 intervention - of which ABP-450 is the first listed.
NCT04871451 names 20 study sites across 11 states, led by Florida, California, Ohio.
Frequently Asked Questions
What is clinical trial NCT04871451 about?
NCT04871451 is a clinical study titled "Extension Study of ABP-19000 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 in Cervical Dystonia". This Open-label Extension trial will evaluate the safety and efficacy of ABP-450 for the treatment of cervical dystonia in adults. The study will enroll 60 patients across approximately 42 sites in the United States from Phase 2 (ABP-19000) trial. Study subjects who had their initial dose of study d...
What is the current status of trial NCT04871451?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 51 participants. The study started on 2021-07-27. Estimated completion is 2023-07-24.
What conditions does trial NCT04871451 study?
This clinical trial studies the following conditions: Cervical Dystonia.
What interventions are being tested in trial NCT04871451?
The interventions under investigation include: ABP-450 (DRUG).
Who is sponsoring clinical trial NCT04871451?
This trial is sponsored by AEON Biopharma, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04871451 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04871451's enrollment target sits among peer trials
51 6th of 15 higher than 10 of 15 other Cervical Dystonia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cervical Dystonia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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