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Extension Study of ABP-19000 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 in Cervical Dystonia
NCT04871451 · View on ClinicalTrials.gov ↗
Study Summary
This Open-label Extension trial will evaluate the safety and efficacy of ABP-450 for the treatment of cervical dystonia in adults. The study will enroll 60 patients across approximately 42 sites in the United States from Phase 2 (ABP-19000) trial. Study subjects who had their initial dose of study drug in the Phase 2 trial, irrespective of treatment allocation, will be eligible to enroll in this OLE study.
Conditions Studied
Interventions
- DRUG ABP-450
Study Locations (20)
Florida
- Infinity Clinical Research LLC — Hollywood
- Brainstorm Research — Miami
- University of South Florida — Tampa
- Neurology One — Winter Park
California
- Parkinson's and Movement Disorder Institute — Fountain Valley
- Neuro Pain Medical Center — Fresno
- Loma Linda University — Loma Linda
Ohio
- The Cleveland Clinic Foundation — Cleveland
- Cleveland Clinic Lou Ruvo Center for Brain Health — Cleveland
- The Orthopedic Foundation — New Albany
Michigan
- Michigan State University — East Lansing
- Quest Research Institute - Hunt - PPDS — Farmington Hills
Tennessee
- Veracity Neuroscience LLC — Memphis
- Vanderbilt University Medical Center — Nashville
Arizona
- Arizona Neuroscience Research — Phoenix
Connecticut
- New England Institute for Neurology and Headache — Stamford
Georgia
- Emory University — Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 51 participants |
| Start Date | 2021-07-27 |
| Est. Completion | 2023-07-24 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04871451
The ClinicalTrials.gov registry entry for NCT04871451 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 51 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AEON Biopharma, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Cervical Dystonia appearing as the primary indexed condition, and to 1 intervention — of which ABP-450 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04871451 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Florida, California, Ohio. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04871451 about?
NCT04871451 is a clinical study titled "Extension Study of ABP-19000 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 in Cervical Dystonia". This Open-label Extension trial will evaluate the safety and efficacy of ABP-450 for the treatment of cervical dystonia in adults. The study will enroll 60 patients across approximately 42 sites in the United States from Phase 2 (ABP-19000) trial. Study subjects who had their initial dose of study d...
What is the current status of trial NCT04871451?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 51 participants. The study started on 2021-07-27. Estimated completion is 2023-07-24.
What conditions does trial NCT04871451 study?
This clinical trial studies the following conditions: Cervical Dystonia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04871451?
The interventions under investigation include: ABP-450 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04871451?
This trial is sponsored by AEON Biopharma, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04871451 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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