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NCT07140874 · ClinicalTrials.gov registry record · Phase 2

Zinc as an Adjunctive Therapy for Cervical Dystonia

A Phase 2 study of Cervical Dystonia, sponsored by University of Florida.

Recruiting
Registry status
Phase 2
Development phase
20
Enrollment target
1
Study location

NCT07140874 is a Phase 2 study of Cervical Dystonia that is actively recruiting participants, run by University of Florida. The registered enrollment target is 20 participants, below the 86-participant average among 15 other Cervical Dystonia trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07140874, a Phase 2 study of Cervical Dystonia, is actively recruiting participants, sponsored by University of Florida.

RECRUITING
Registry status
Phase 2
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to evaluate if supplemental zinc can prolong the duration of benefit of botulinum toxin injections in cervical dystonia patients receiving care at the University of Florida. The main aims are: 1. To evaluate the efficacy of zinc citrate supplementation in prolonging the duration of symptom relief provided by botulinum toxin type A (Botox) injections in cervical dystonia patients. 2. To assess the safety and tolerability of zinc supplementation in this patient population. 3. To analyze the potential influence of zinc supplementation on the quality of life and functional outcomes in cervical dystonia patients receiving Botox. Researchers will compare zinc citrate to a placebo (a look-alike substance that contains no active drug) to see if zinc works to extend the effects of Botox. Participants will: Take zinc citrate or a placebo every day for 3 months, then cross over to the alternative treatment for another 3 months. Visit the clinic every 3 months for Botox injections, check ups and surveys.

Conditions Studied

Cervical Dystonia

Interventions

  • DRUG Placebo
  • DRUG Zinc citrate

Study Locations (1)

Florida

  • Norman Fixel Institute for Neurological Diseases - Gainesville

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2026-02-20
Est. Completion 2026-12-31
Phase Phase 2

Sponsor

University of Florida

1,106 total trials

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What the Registry Record Tells You About NCT07140874

The ClinicalTrials.gov registry entry for NCT07140874 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 86-participant average among 15 other Cervical Dystonia trials with a reported enrollment target (77% lower). The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cervical Dystonia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT07140874 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT07140874 about?

NCT07140874 is a clinical study titled "Zinc as an Adjunctive Therapy for Cervical Dystonia". The goal of this clinical trial is to evaluate if supplemental zinc can prolong the duration of benefit of botulinum toxin injections in cervical dystonia patients receiving care at the University of Florida. The main aims are: 1. To evaluate the efficacy of zinc citrate supplementation in prolong...

What is the current status of trial NCT07140874?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2026-02-20. Estimated completion is 2026-12-31.

What conditions does trial NCT07140874 study?

This clinical trial studies the following conditions: Cervical Dystonia.

What interventions are being tested in trial NCT07140874?

The interventions under investigation include: Placebo (DRUG), Zinc citrate (DRUG).

Who is sponsoring clinical trial NCT07140874?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07140874 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.