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NCT02131467 · ClinicalTrials.gov registry record · Phase 1
Safety and Tolerability of Perampanel in Cervical Dystonia
A Phase 1 study of Cervical Dystonia, sponsored by University Health Network, Toronto.
- Completed
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
- 5
- Study locations
NCT02131467 is a Phase 1 study of Cervical Dystonia that has completed, run by University Health Network, Toronto. The registered enrollment target is 25 participants, below the 85-participant average among 15 other Cervical Dystonia trials with a reported enrollment target (71% lower). The trial reports 5 study locations across 5 states.
The verdict
NCT02131467, a Phase 1 study of Cervical Dystonia, has completed, sponsored by University Health Network, Toronto.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
- 5
- Study locations
Study Summary
Cervical dystonia (CD) is the most common focal dystonia. Currently there are no effective oral medications for the treatment of CD. While botulinum toxin injections improve symptoms, they require repeated injections by a trained physician and some patients stop responding to injections or never respond at all. Therefore, alternative treatment options for CD are needed. One new agent is a drug that targets glutamate receptors that are thought to be involved dystonia. This drug, perampanel, was originally developed for epilepsy and is licensed for use in the USA and Canada for treating epilepsy. The purpose of this study is to test the effectiveness of perampanel in treating the symptoms of CD.
Conditions Studied
Interventions
- DRUG Perampanel
Study Locations (5)
Georgia
- Emory University School of Medicine - Atlanta
Illinois
- Rush University Medical Center - Chicago
New York
- Beth Israel Medical Center - New York
Ohio
- Cleveland Clinic - Cleveland
Ontario
- Toronto Western Hospital - Toronto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2017-09-01 |
| Est. Completion | 2020-02-28 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02131467
The ClinicalTrials.gov registry entry for NCT02131467 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 85-participant average among 15 other Cervical Dystonia trials with a reported enrollment target (71% lower). The listed sponsor is University Health Network, Toronto, which has 23 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Cervical Dystonia appearing as the primary indexed condition, and to 1 intervention - of which Perampanel is the first listed.
NCT02131467 reports 5 study locations spanning 5 distinct geographic areas - top geographies include Georgia, Illinois, New York.
Frequently Asked Questions
What is clinical trial NCT02131467 about?
NCT02131467 is a clinical study titled "Safety and Tolerability of Perampanel in Cervical Dystonia". Cervical dystonia (CD) is the most common focal dystonia. Currently there are no effective oral medications for the treatment of CD. While botulinum toxin injections improve symptoms, they require repeated injections by a trained physician and some patients stop responding to injections or never res...
What is the current status of trial NCT02131467?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2017-09-01. Estimated completion is 2020-02-28.
What conditions does trial NCT02131467 study?
This clinical trial studies the following conditions: Cervical Dystonia.
What interventions are being tested in trial NCT02131467?
The interventions under investigation include: Perampanel (DRUG).
Who is sponsoring clinical trial NCT02131467?
This trial is sponsored by University Health Network, Toronto, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02131467 being conducted?
This trial has 5 study locations across Georgia, Illinois, New York, Ohio, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.