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NCT04846829 · ClinicalTrials.gov registry record · Early Phase 1

Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD)

A Early Phase 1 study of Major Depressive Disorder, sponsored by University of California, Los Angeles.

Active
Registry status
Early Phase 1
Development phase
30
Enrollment target
1
Study location

NCT04846829 is a Early Phase 1 study of Major Depressive Disorder that is active but no longer recruiting, run by University of California, Los Angeles. The registered enrollment target is 30 participants, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04846829, a Early Phase 1 study of Major Depressive Disorder, is active but no longer recruiting, sponsored by University of California, Los Angeles.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

This study will recruit 30 subjects diagnosed with Major Depressive Disorder (MDD). Subjects will be recieve one infusion treatment of citalopram or placebo and 10 treatments of a form of transcranial magnetic stimulation, theta burst stimulation (TBS). Subjects will also undergo brain scans, quantitative electroencephalography (qEEG) brain activity recordings, and mood surveys. Study activities will be performed over the course of 4 weeks.

Conditions Studied

Interventions

  • DRUG Placebo
  • DEVICE intermittent theta burst stimulation
  • DRUG intravenous citalopram hydrochloride (CIT)
  • DEVICE continuous theta burst stimulation

Study Locations (1)

California

  • UCLA Depression Research and Clinic Program - Los Angeles

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2017-04-24
Est. Completion 2028-04-24
Phase Early Phase 1

What the Registry Record Tells You About NCT04846829

The ClinicalTrials.gov registry entry for NCT04846829 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (92% lower). The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Major Depressive Disorder appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT04846829 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT04846829 about?

NCT04846829 is a clinical study titled "Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD)". This study will recruit 30 subjects diagnosed with Major Depressive Disorder (MDD). Subjects will be recieve one infusion treatment of citalopram or placebo and 10 treatments of a form of transcranial magnetic stimulation, theta burst stimulation (TBS). Subjects will also undergo brain scans, quanti...

What is the current status of trial NCT04846829?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 30 participants. The study started on 2017-04-24. Estimated completion is 2028-04-24.

What conditions does trial NCT04846829 study?

This clinical trial studies the following conditions: Major Depressive Disorder.

What interventions are being tested in trial NCT04846829?

The interventions under investigation include: Placebo (DRUG), intermittent theta burst stimulation (DEVICE), intravenous citalopram hydrochloride (CIT) (DRUG), continuous theta burst stimulation (DEVICE).

Who is sponsoring clinical trial NCT04846829?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04846829 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.