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NCT04780009 · ClinicalTrials.gov registry record
Loupe-Based Intraoperative Fluorescence Imaging
A clinical trial of Glioblastoma Multiforme and Anaplastic Astrocytoma, sponsored by Guoqiang Yu.
- Recruiting
- Registry status
- 30
- Enrollment target
- 1
- Study location
NCT04780009: Recruiting study of Glioblastoma Multiforme and Anaplastic Astrocytoma, sponsored by Guoqiang Yu.
NCT04780009 is a study of Glioblastoma Multiforme and Anaplastic Astrocytoma that is actively recruiting participants, run by Guoqiang Yu. The registered enrollment target is 30 participants, below the 97-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04780009, a study of Glioblastoma Multiforme and Anaplastic Astrocytoma, is actively recruiting participants, sponsored by Guoqiang Yu.
- RECRUITING
- Registry status
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA) are the most common primary malignant brain tumors. Survival of patients with these brain tumors is directly related to the extent of resection. Consequently, a great deal of effort has been directed at developing techniques and technologies that allow more extensive, safe resections. This study will test a loupe-based wearable device in the clinical setting and compare its accuracy with a large operative microscope to identify tumor tissues. Postoperative histopathological analysis on tumor tissues will be used as gold standards for comparison. The outcome from this study will be a low-cost, miniaturized, easy-to-operate, loupe-based fluorescence imaging device for intraoperative guidance of brain tumor resection with the same level of accuracy as the large microscope.
Primary Outcome
The proportion of samples that are histologically confirmed as tumor-positive among all fluorescent samples will be calculated.
Conditions Studied
Study Locations (1)
Kentucky
- University of Kentucky - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2017-11-17 |
| Est. Completion | 2026-06 |
What NCT04780009 shows while recruiting
NCT04780009 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 97-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (69% lower).
The record links to 2 conditions, with Glioblastoma Multiforme appearing as the primary indexed condition, and to 0 interventions.
NCT04780009 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT04780009 about?
NCT04780009 is a clinical study titled "Loupe-Based Intraoperative Fluorescence Imaging". Glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA) are the most common primary malignant brain tumors. Survival of patients with these brain tumors is directly related to the extent of resection. Consequently, a great deal of effort has been directed at developing techniques and technolog...
What is the current status of trial NCT04780009?
This trial is currently recruiting. The enrollment target is 30 participants. The study started on 2017-11-17. Estimated completion is 2026-06.
What conditions does trial NCT04780009 study?
This clinical trial studies the following conditions: Glioblastoma Multiforme, Anaplastic Astrocytoma.
Who is sponsoring clinical trial NCT04780009?
This trial is sponsored by Guoqiang Yu, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04780009 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04780009's enrollment target sits among peer trials
30 61st of 88 higher than 26 of 88 other Glioblastoma Multiforme trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Glioblastoma Multiforme trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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