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NCT04756076 · ClinicalTrials.gov registry record
Study Roles of Heavy Metals and Essential Metal Dyshomeostasis in Pulmonary Arterial Hypertension Patients
A clinical trial of Pulmonary Hypertension and Metal Poison, sponsored by Jiapeng Huang.
- Recruiting
- Registry status
- 110
- Enrollment target
- 1
- Study location
NCT04756076: Recruiting study of Pulmonary Hypertension and Metal Poison, sponsored by Jiapeng Huang.
NCT04756076 is a study of Pulmonary Hypertension and Metal Poison that is actively recruiting participants, run by Jiapeng Huang. The registered enrollment target is 110 participants, below the 612-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04756076, a study of Pulmonary Hypertension and Metal Poison, is actively recruiting participants, sponsored by Jiapeng Huang.
- RECRUITING
- Registry status
- 110 participants
- Enrollment target
- 1
- Study location
Study Summary
Investigators plan to recruit 50 PAH patients from UofL PAH Clinic, with various degrees of severity (25 intermediate risk patients and 20 high risk patients) and 10 age and gender matched controls. PAH patients are evaluated at least every 6 months by the PAH Clinic and blood/urine samples will be obtained at each office visit. Blood, plasma and urine samples will be used to measure 31 metal levels including heavy metals (cadmium, arsenic, cobalt, lead etc.) and essential metals (calcium, copper, iron, zinc, potassium etc.) by the with ICP-MS via the service of ITEMFC. Interactions among the 31 metals in PAH patients, metal concentration differences between intermediate risk PAH, high risk PAH and control groups, the correlation between metal concentrations and the etiology, severity, duration, treatment, and progression of PAH/RV dysfunction over 12 months will be analyzed by CIEHS Biostatistics and Informatics Facility Core.
Primary Outcome
Metal levels in control and pulmonary hypertension groups
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Metal level measurements
Study Locations (1)
Kentucky
- University of Louisville Health - Louisville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2020-12-02 |
| Est. Completion | 2029-12-31 |
What NCT04756076 shows while recruiting
NCT04756076 is an observational study that tracks outcomes without assigning an intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap, below the 612-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (82% lower).
The record links to 2 conditions, with Pulmonary Hypertension appearing as the primary indexed condition, and to 1 intervention - of which Metal level measurements is the first listed.
NCT04756076 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT04756076 about?
NCT04756076 is a clinical study titled "Study Roles of Heavy Metals and Essential Metal Dyshomeostasis in Pulmonary Arterial Hypertension Patients". Investigators plan to recruit 50 PAH patients from UofL PAH Clinic, with various degrees of severity (25 intermediate risk patients and 20 high risk patients) and 10 age and gender matched controls. PAH patients are evaluated at least every 6 months by the PAH Clinic and blood/urine samples will be ...
What is the current status of trial NCT04756076?
This trial is currently recruiting. The enrollment target is 110 participants. The study started on 2020-12-02. Estimated completion is 2029-12-31.
What conditions does trial NCT04756076 study?
This clinical trial studies the following conditions: Pulmonary Hypertension, Metal Poison.
What interventions are being tested in trial NCT04756076?
The interventions under investigation include: Metal level measurements (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04756076?
This trial is sponsored by Jiapeng Huang, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04756076 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pulmonary Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04756076's enrollment target sits among peer trials
110 31st of 72 higher than 42 of 72 other Pulmonary Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pulmonary Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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