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NCT04741698 · ClinicalTrials.gov registry record · Phase 1

Propranolol for Protracted Labor

A Phase 1 study, sponsored by Christiana Care Health Services.

Completed
Registry status
Phase 1
Development phase
80
Enrollment target

NCT04741698 is a Phase 1 study that has completed, run by Christiana Care Health Services. The registered enrollment target is 80 participants.

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The verdict

NCT04741698, a Phase 1 study, has completed, sponsored by Christiana Care Health Services.

COMPLETED
Registry status
Phase 1
Development phase
80 participants
Enrollment target

Study Summary

Induction of labor is one of the most common procedures performed on labor and delivery. In the United States, more than 20 percent of pregnant women undergo an induction of labor \[1\]. There is data from small, randomized studies that demonstrates the effectiveness of propranolol, a non-selective beta-blocker, for labor augmentation. This literature suggests a decrease in the amount of time to delivery and a possible reduction in cesarean section rates when propranolol is used in conjunction with oxytocin for induction of labor compared to oxytocin alone \[2-8\]. Alpha- and beta-adrenergic receptors have been identified in the human myometrium. Propranolol has been shown in studies to enhance uterine contractions and may be a useful tool in this population of women. Therefore, the purpose of this study is to assess whether the administration of propranolol at time of labor dystocia reduces time to delivery.

Interventions

  • DRUG Propranolol

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2021-07-27
Est. Completion 2022-07-01
Phase Phase 1

Sponsor

Christiana Care Health Services

82 total trials

What the Registry Record Tells You About NCT04741698

The ClinicalTrials.gov registry entry for NCT04741698 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Christiana Care Health Services, which has 82 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Propranolol is the first listed.

NCT04741698 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04741698 about?

NCT04741698 is a clinical study titled "Propranolol for Protracted Labor". Induction of labor is one of the most common procedures performed on labor and delivery. In the United States, more than 20 percent of pregnant women undergo an induction of labor \[1\]. There is data from small, randomized studies that demonstrates the effectiveness of propranolol, a non-selective...

What is the current status of trial NCT04741698?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2021-07-27. Estimated completion is 2022-07-01.

What interventions are being tested in trial NCT04741698?

The interventions under investigation include: Propranolol (DRUG).

Who is sponsoring clinical trial NCT04741698?

This trial is sponsored by Christiana Care Health Services, which has 82 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.