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NCT04739072 · ClinicalTrials.gov registry record
Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study
A clinical trial of Colorectal Adenocarcinoma and Stage III Colorectal Cancer AJCC v8, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- 1,000
- Enrollment target
- 10
- Study locations
NCT04739072: Recruiting study of Colorectal Adenocarcinoma and Stage III Colorectal Cancer AJCC v8, sponsored by M.D. Anderson Cancer Center.
NCT04739072 is a study of Colorectal Adenocarcinoma and Stage III Colorectal Cancer AJCC v8 that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 1,000 participants, above the 266-participant average among 19 other Colorectal Adenocarcinoma trials with a reported enrollment target (276% higher). The trial reports 10 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04739072, a study of Colorectal Adenocarcinoma and Stage III Colorectal Cancer AJCC v8, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
- 10
- Study locations
Study Summary
This study investigates if circulating tumor DNA (ctDNA) and other tumor-related molecules/chemicals released in the blood can help doctors predict if colorectal cancer may come back or spread. Tumors shed DNA and other cancer related chemicals into the blood that can be identified and studied further to provide information about the cancer. Information gathered from this study may help researchers better understand if ctDNA found in the blood can predict whether colorectal cancer may come back or spread.
Primary Outcome
To detect circulating tumor DNA (ctDNA) in plasma samples from patients with colorectal cancer (CRC) who have completed curative therapies (i.e. minimal residual disease) towards predicting recurrence earlier than the current standard of care utilizing the CRC23 assay and the LUNAR assay from Guardant Health technology.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Electronic Health Record Review
Study Locations (10)
Texas
- UT Southwestern/Simmons Cancer Center-Dallas - Dallas
- Houston Methodist Cancer Center - Houston
- M D Anderson Cancer Center - Houston
- UT Health San Antonio MD Anderson Cancer Center - San Antonio
- Baylor Scott & White Research Institute - Temple
Arizona
- Banner - MD Anderson Cancer Center - Gilbert
Florida
- Baptist- MD Anderson Cancer Center - Jacksonville
Hawaii
- The Queen's Medical Center - Honolulu
Idaho
- St. Luke's Cancer Institute - Boise
New Jersey
- Cooper Hospital UNIV MED CTR. - Camden
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2019-11-22 |
| Est. Completion | 2025-12-31 |
What NCT04739072 shows while recruiting
NCT04739072 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, above the 266-participant average among 19 other Colorectal Adenocarcinoma trials with a reported enrollment target (276% higher).
The record links to 10 conditions, with Colorectal Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions - of which Biospecimen Collection is the first listed.
NCT04739072 lists 10 locations in 6 states (Texas, Arizona, Florida).
Frequently Asked Questions
What is clinical trial NCT04739072 about?
NCT04739072 is a clinical study titled "Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study". This study investigates if circulating tumor DNA (ctDNA) and other tumor-related molecules/chemicals released in the blood can help doctors predict if colorectal cancer may come back or spread. Tumors shed DNA and other cancer related chemicals into the blood that can be identified and studied furth...
What is the current status of trial NCT04739072?
This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2019-11-22. Estimated completion is 2025-12-31.
What conditions does trial NCT04739072 study?
This clinical trial studies the following conditions: Colorectal Adenocarcinoma, Stage III Colorectal Cancer AJCC v8, Stage II Colorectal Cancer AJCC v8, Stage IIIA Colorectal Cancer AJCC v8, Stage IIIB Colorectal Cancer AJCC v8.
What interventions are being tested in trial NCT04739072?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Electronic Health Record Review (OTHER).
Who is sponsoring clinical trial NCT04739072?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04739072 being conducted?
This trial has 10 study locations across Arizona, Florida, Hawaii, Idaho, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04739072's enrollment target sits among peer trials
1,000 2nd of 19 the highest of 19 other Colorectal Adenocarcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colorectal Adenocarcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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