Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Type O Whole Blood and Assessment of Age During Prehospital Resuscitation Trial
NCT04684719 · View on ClinicalTrials.gov ↗
Study Summary
Open label, multi-center, pre-hospital randomized trial utilizing 10 level-1 trauma centers designed to determine the efficacy and safety of low titer whole blood resuscitation as compared to standard of care resuscitation in patients at risk of hemorrhagic shock and to appropriately characterize the hemostatic competency of whole blood relative to its age.
Conditions Studied
Interventions
- BIOLOGICAL low titer whole blood
- BIOLOGICAL Standard Care
Study Locations (10)
Ohio
- University of Cincinatti — Cincinnati
- Metrohealth Systems — Cleveland
Tennessee
- University of Tennessee Medical Center — Knoxville
- Vanderbilt University Medical Center — Nashville
Alabama
- University of Alabama at Birmingham — Birmingham
Kentucky
- University of Louisville — Louisville
Mississippi
- University of Mississippi Medical Center (UMMC) — Jackson
Pennsylvania
- University of Pittsburgh — Pittsburgh
Texas
- University of Texas Health Science Center at Houston — Houston
Washington
- University of Washington — Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,020 participants |
| Start Date | 2022-04-19 |
| Est. Completion | 2025-08-12 |
| Phase | Phase 3 |
Interested in This Trial?
Always speak with your doctor before enrolling in a clinical trial.
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04684719
The ClinicalTrials.gov registry entry for NCT04684719 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,020 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jason Sperry, which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Traumatic Injury appearing as the primary indexed condition, and to 2 interventions — of which low titer whole blood is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04684719 reports 10 study locations spanning 8 distinct geographic areas — top geographies include Ohio, Tennessee, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04684719 about?
NCT04684719 is a clinical study titled "Type O Whole Blood and Assessment of Age During Prehospital Resuscitation Trial". Open label, multi-center, pre-hospital randomized trial utilizing 10 level-1 trauma centers designed to determine the efficacy and safety of low titer whole blood resuscitation as compared to standard of care resuscitation in patients at risk of hemorrhagic shock and to appropriately characterize th...
What is the current status of trial NCT04684719?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,020 participants. The study started on 2022-04-19. Estimated completion is 2025-08-12.
What conditions does trial NCT04684719 study?
This clinical trial studies the following conditions: Traumatic Injury, Hemorrhagic Shock. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04684719?
The interventions under investigation include: low titer whole blood (BIOLOGICAL), Standard Care (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04684719?
This trial is sponsored by Jason Sperry, which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04684719 being conducted?
This trial has 10 study locations across Alabama, Kentucky, Mississippi, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How Clinical Trials Work
Understand phases 1-4, trial design, randomization, and the informed consent process.
Patient Rights in Clinical Trials
Your rights as a participant: consent, withdrawal, privacy, and who to contact.
Finding the Right Clinical Trial
A practical guide to searching trials, understanding eligibility, and evaluating options.
All Guides
Browse our complete library of clinical trial educational resources.
Read our methodology — how this data is sourced, computed, and verified.