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NCT05437575 · ClinicalTrials.gov registry record · Phase 3
Prehospital Analgesia INtervention Trial (PAIN)
A Phase 3 study of Traumatic Injury, sponsored by Jason Sperry.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 994
- Enrollment target
- 11
- Study locations
NCT05437575: Recruiting Phase 3 study of Traumatic Injury, sponsored by Jason Sperry.
NCT05437575 is a Phase 3 study of Traumatic Injury that is actively recruiting participants, run by Jason Sperry. The registered enrollment target is 994 participants, above the 297-participant average among 7 other Traumatic Injury trials with a reported enrollment target (235% higher). The trial reports 11 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05437575, a Phase 3 study of Traumatic Injury, is actively recruiting participants, sponsored by Jason Sperry.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 994 participants
- Enrollment target
- 11
- Study locations
Study Summary
The Prehospital Analgesia INtervention trial (PAIN) is a proposed 4 year (3-year enrollment) multicenter, prehospital, randomized, double-blind, clinical trial that will enroll approximately 994 patients at select LITES Network sites. The objective is to perform a prospective, interventional, randomized trial among prehospital trauma patients with compensated shock (SI≥0.9 or HR ≥115) and an indication for pain management, comparing patient centered outcomes following prehospital administration of ketamine hydrochloride versus fentanyl citrate.
Primary Outcome
All cause mortality within 24 hours from time of trauma bay arrival
Conditions Studied
Interventions
- DRUG Ketamine Hydrochloride
- DRUG Fentanyl Citrate
Study Locations (11)
Pennsylvania
- Allegheny Health Network (AHN) Allegheny General Hospital - Pittsburgh
- University of Pittsburgh - Pittsburgh
- Guthrie Robert Packer Hospital - Sayre
California
- University of California, San Diego - San Diego
- Zuckerberg San Francisco General Hospital - San Francisco
New Jersey
- Cooper University Health Care - Camden
North Carolina
- Atrium Health and Carolinas Medical Center - Charlotte
Ohio
- University of Cincinnati - Cincinnati
Utah
- University of Utah - Salt Lake City
Vermont
- The University of Vermont Larner College of Medicine - Burlington
Wisconsin
- Medical College of Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 994 participants |
| Start Date | 2023-11-27 |
| Est. Completion | 2029-07 |
| Phase | Phase 3 |
What NCT05437575 shows while recruiting
NCT05437575 is an interventional study that assigns participants to a tested intervention. The registered 994 participants enrollment target is mid-sized for trials with a published cap, above the 297-participant average among 7 other Traumatic Injury trials with a reported enrollment target (235% higher).
The record links to 1 condition, with Traumatic Injury appearing as the primary indexed condition, and to 2 interventions - of which Ketamine Hydrochloride is the first listed.
NCT05437575 lists 11 locations in 8 states (Pennsylvania, California, New Jersey).
Frequently Asked Questions
What is clinical trial NCT05437575 about?
NCT05437575 is a clinical study titled "Prehospital Analgesia INtervention Trial (PAIN)". The Prehospital Analgesia INtervention trial (PAIN) is a proposed 4 year (3-year enrollment) multicenter, prehospital, randomized, double-blind, clinical trial that will enroll approximately 994 patients at select LITES Network sites. The objective is to perform a prospective, interventional, random...
What is the current status of trial NCT05437575?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 994 participants. The study started on 2023-11-27. Estimated completion is 2029-07.
What conditions does trial NCT05437575 study?
This clinical trial studies the following conditions: Traumatic Injury.
What interventions are being tested in trial NCT05437575?
The interventions under investigation include: Ketamine Hydrochloride (DRUG), Fentanyl Citrate (DRUG).
Who is sponsoring clinical trial NCT05437575?
This trial is sponsored by Jason Sperry, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05437575 being conducted?
This trial has 11 study locations across California, New Jersey, North Carolina, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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