Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04663802 · ClinicalTrials.gov registry record · NA
Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study
A NA study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- NA
- Development phase
- 7,342
- Enrollment target
NCT04663802: Completed NA study, sponsored by University of Pennsylvania.
NCT04663802 is a NA study that has completed, run by University of Pennsylvania. The registered enrollment target is 7,342 participants, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (423% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04663802, a NA study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- NA
- Development phase
- 7,342 participants
- Enrollment target
Study Summary
This study is a large pragmatic stepped-wedge trial of electronic health record (EHR)-based implementation strategies informed by behavioral economic principles to increase lung-protective ventilation (LPV) utilization among all mechanically ventilated (MV), adult patients. The study will compare the standard approach to managing MV across 12 study Intensive Care Units (ICUs) within University of Pennsylvania Health System (UPHS) versus interventions prompting physicians and respiratory therapists (RTs) to employ LPV settings promote LPV utilization among all MV patients.
Primary Outcome
percentage of time that a patient is exposed to tidal volume \<6.5 cc/kg ideal body weight
Interventions
- BEHAVIORAL Default order set
- BEHAVIORAL Physician-targeted accountable justification
- BEHAVIORAL Respiratory therapist (RT)-targeted accountable justification
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7,342 participants |
| Start Date | 2021-02-22 |
| Est. Completion | 2023-12-15 |
| Phase | NA |
What the finished NCT04663802 record still lists
NCT04663802 is an interventional study that assigns participants to a tested intervention. Its 7,342 participants enrollment target places it among the larger protocols in the corpus, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (423% higher).
The record links to 0 conditions, and to 3 interventions - of which Default order set is the first listed.
NCT04663802 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04663802 about?
NCT04663802 is a clinical study titled "Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study". This study is a large pragmatic stepped-wedge trial of electronic health record (EHR)-based implementation strategies informed by behavioral economic principles to increase lung-protective ventilation (LPV) utilization among all mechanically ventilated (MV), adult patients. The study will compare th...
What is the current status of trial NCT04663802?
This trial is currently completed. It is a NA study. The enrollment target is 7,342 participants. The study started on 2021-02-22. Estimated completion is 2023-12-15.
What interventions are being tested in trial NCT04663802?
The interventions under investigation include: Default order set (BEHAVIORAL), Physician-targeted accountable justification (BEHAVIORAL), Respiratory therapist (RT)-targeted accountable justification (BEHAVIORAL).
Who is sponsoring clinical trial NCT04663802?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04663802's enrollment target sits among peer trials
7,342 20th of 2000 higher than 1,981 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02915198 · 7,410 participants · Phase 4
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes
- NCT05049837 · 7,200 participants
PROSPECT - Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification
- NCT06714929 · 7,200 participants · NA
Advancing Water Security: A Community Participatory School-Based Hydration Intervention
- NCT00439049 · 7,500 participants
Substance Abuse Pre-Treatment Screening Study
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI