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NCT04657042 · ClinicalTrials.gov registry record
4D-MRI for Precision Medicine
A clinical trial of Lung Cancer and Healthy Volunteers, sponsored by University of Virginia.
- Recruiting
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT04657042: Recruiting study of Lung Cancer and Healthy Volunteers, sponsored by University of Virginia.
NCT04657042 is a study of Lung Cancer and Healthy Volunteers that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 100 participants, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04657042, a study of Lung Cancer and Healthy Volunteers, is actively recruiting participants, sponsored by University of Virginia.
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to develop new ways to make medical images of the lungs and liver of adults using a technique called four-dimensional magnetic resonance imaging (4D-MRI). This technique produces three-dimensional movies of the inside of the chest and abdomen while the patient is breathing. (The fourth dimension is time!) This new way of medical imaging is being developed to help cancer patients undergoing radiation therapy. Radiation therapy is used to treat cancerous tumors. For radiation therapy to be effective, the precise size, shape, and location of the tumor within the body must be known. A particular difficulty for radiation treatment of lung and liver cancer is that the tumor moves during treatment because the patient is breathing. Therefore, tumor motion must also be incorporated into the treatment plan. This study aims to improve radiation treatment planning through better targeting and dose estimation based on 4D-MRI. Before this new imaging method can be used for radiation treatment planning, it must be tested in living, breathing volunteers.
Primary Outcome
General 4D-MRI image quality will be assessed based on signal-to-noise ratio, number of distinct images per breathing cycle, total necessary imaging time, and image quality index.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Magnetic Resonance Imaging
Study Locations (1)
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2020-11-05 |
| Est. Completion | 2030-12-31 |
What NCT04657042 shows while recruiting
NCT04657042 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (89% lower).
The record links to 3 conditions, with Lung Cancer appearing as the primary indexed condition, and to 1 intervention - of which Magnetic Resonance Imaging is the first listed.
NCT04657042 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT04657042 about?
NCT04657042 is a clinical study titled "4D-MRI for Precision Medicine". The purpose of this study is to develop new ways to make medical images of the lungs and liver of adults using a technique called four-dimensional magnetic resonance imaging (4D-MRI). This technique produces three-dimensional movies of the inside of the chest and abdomen while the patient is breathi...
What is the current status of trial NCT04657042?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2020-11-05. Estimated completion is 2030-12-31.
What conditions does trial NCT04657042 study?
This clinical trial studies the following conditions: Lung Cancer, Healthy Volunteers, Liver Cancer.
What interventions are being tested in trial NCT04657042?
The interventions under investigation include: Magnetic Resonance Imaging (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04657042?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04657042 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lung Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04657042's enrollment target sits among peer trials
100 186th of 409 higher than 212 of 409 other Lung Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lung Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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