Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04615260 · ClinicalTrials.gov registry record · NA
Rate of Bony Fusion Using NanoBone® Synthetic Bone Graft Versus Local Autologous Bone Graft.
A NA study of Degenerative Disc Disease and Spondylolisthesis, sponsored by Artoss.
- Active
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT04615260: Active NA study of Degenerative Disc Disease and Spondylolisthesis, sponsored by Artoss.
NCT04615260 is a NA study of Degenerative Disc Disease and Spondylolisthesis that is active but no longer recruiting, run by Artoss. The registered enrollment target is 40 participants, below the 168-participant average among 42 other Degenerative Disc Disease trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04615260, a NA study of Degenerative Disc Disease and Spondylolisthesis, is active but no longer recruiting, sponsored by Artoss.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The objectives of this longitudinal study are to assess and measure fusion status (fused or not fused) and rate of bony fusion using NanoBone® Synthetic Bone Graft in patients requiring one to two level lumbar posterolateral fusion procedures with or without commercially available rigid spinal instrumentation. Our hypothesis is that the Nanobone synthetic bone graft will be as effective at creating a fusion in the lumbar spine as compared with a local bone graft. Each subject will serve as their own control during this study, as patients will receive the Nanobone graft on the right side of their spine and the local bone graft on their left side.
Primary Outcome
Fusion will be defined as: * Evidence of bridging trabecular bone between the transverse processes of the involved vertebral bodies * Translational motion \< 3.5mm on flexion/extension radiographs; and * Angular motion \<5 degrees on flexion/extension radiographs.
Conditions Studied
Interventions
- DEVICE NanoBone
Study Locations (1)
Massachusetts
- UMass Memorial Health Care - Worcester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-07-19 |
| Est. Completion | 2025-04-30 |
| Phase | NA |
What the registry record for NCT04615260 still lists
NCT04615260 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 168-participant average among 42 other Degenerative Disc Disease trials with a reported enrollment target (76% lower).
The record links to 2 conditions, with Degenerative Disc Disease appearing as the primary indexed condition, and to 1 intervention - of which NanoBone is the first listed.
NCT04615260 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04615260 about?
NCT04615260 is a clinical study titled "Rate of Bony Fusion Using NanoBone® Synthetic Bone Graft Versus Local Autologous Bone Graft.". The objectives of this longitudinal study are to assess and measure fusion status (fused or not fused) and rate of bony fusion using NanoBone® Synthetic Bone Graft in patients requiring one to two level lumbar posterolateral fusion procedures with or without commercially available rigid spinal instr...
What is the current status of trial NCT04615260?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2021-07-19. Estimated completion is 2025-04-30.
What conditions does trial NCT04615260 study?
This clinical trial studies the following conditions: Degenerative Disc Disease, Spondylolisthesis.
What interventions are being tested in trial NCT04615260?
The interventions under investigation include: NanoBone (DEVICE).
Who is sponsoring clinical trial NCT04615260?
This trial is sponsored by Artoss, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04615260 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Degenerative Disc Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04615260's enrollment target sits among peer trials
40 33rd of 42 higher than 9 of 42 other Degenerative Disc Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Degenerative Disc Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Investigation of DEXA-C Anterior Cervical Interbody System
RECRUITING · NA
-
Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion
RECRUITING · NA
-
Trial for Treating Painful Degenerative Disc Disease
RECRUITING · NA
-
Evaluation of Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine.
RECRUITING · NA
-
MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
RECRUITING · NA
-
ACDF Using Structural Allograft vs. Tritanium C
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01306019 · 40 participants · Phase 1
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- NCT01608152 · 40 participants
Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
- NCT01668082 · 40 participants · NA
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- NCT02015013 · 40 participants · Phase 2
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI