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NCT04611347 · ClinicalTrials.gov registry record · Phase 2
Is Topical CBD Effective in Treating Thumb Joint Arthritis
A Phase 2 study of CBD and Hand Osteoarthritis, sponsored by University of Virginia.
- Completed
- Registry status
- Phase 2
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT04611347: Completed Phase 2 study of CBD and Hand Osteoarthritis, sponsored by University of Virginia.
NCT04611347 is a Phase 2 study of CBD and Hand Osteoarthritis that has completed, run by University of Virginia. The registered enrollment target is 18 participants, below the 65-participant average among 8 other CBD trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04611347, a Phase 2 study of CBD and Hand Osteoarthritis, has completed, sponsored by University of Virginia.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
Rationale: CBD is commonly being used as an over-the-counter treatment for arthritis-related pain, however no clinical trial has been performed to establish efficacy. Hypothesis: CBD is more effective than placebo for relieving pain and improving patient-reported outcomes for thumb basal joint arthritis. Study Design: The study design with be a double-blind, randomized controlled trial with crossover. Treatment will be blinded to the subjects and investigators. Patients will be randomly assigned 2 weeks of the CBD or control and then crossover to the other condition for 2 additional weeks. Patients will apply the cream at the thumb base twice daily for 1 hour. Subjects will be advised to observe for physiologic changes, skin changes, or other adverse effects.
Primary Outcome
Grip strength, kg.
Conditions Studied
Interventions
- DRUG CBD
- DRUG Shea Butter
Study Locations (1)
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2020-07-28 |
| Est. Completion | 2022-05-11 |
| Phase | Phase 2 |
What the finished NCT04611347 record still lists
NCT04611347 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 65-participant average among 8 other CBD trials with a reported enrollment target (72% lower).
The record links to 2 conditions, with CBD appearing as the primary indexed condition, and to 2 interventions - of which CBD is the first listed.
NCT04611347 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT04611347 about?
NCT04611347 is a clinical study titled "Is Topical CBD Effective in Treating Thumb Joint Arthritis". Rationale: CBD is commonly being used as an over-the-counter treatment for arthritis-related pain, however no clinical trial has been performed to establish efficacy. Hypothesis: CBD is more effective than placebo for relieving pain and improving patient-reported outcomes for thumb basal joint arth...
What is the current status of trial NCT04611347?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2020-07-28. Estimated completion is 2022-05-11.
What conditions does trial NCT04611347 study?
This clinical trial studies the following conditions: CBD, Hand Osteoarthritis.
What interventions are being tested in trial NCT04611347?
The interventions under investigation include: CBD (DRUG), Shea Butter (DRUG).
Who is sponsoring clinical trial NCT04611347?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04611347 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT04611347's enrollment target sits among peer trials
18 8th of 8 higher than 1 of 8 other CBD trials
participants (enrollment target), bucketed by value
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