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NCT04593875 · ClinicalTrials.gov registry record · NA
LIFUP for Treatment of Motor Deficits in Parkinson's Disease
A NA study, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- NA
- Development phase
- 31
- Enrollment target
NCT04593875: Completed NA study, sponsored by University of California, Los Angeles.
NCT04593875 is a NA study that has completed, run by University of California, Los Angeles. The registered enrollment target is 31 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04593875, a NA study, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- NA
- Development phase
- 31 participants
- Enrollment target
Study Summary
The study will test the feasibility of using Low Intensity Focused Ultrasound Pulsation (LIFUP) to treat motor symptoms in Parkinson's Disease (PD). LIFUP is a new technique that can increase brain activity in highly specific target areas and is MRI compatible. Thus, in real-time, it is possible to directly observe how LIFUP changes the brain areas important in PD by measuring its effects on brain activity, blood flow, and brain connectivity. If successful, this research will mark the first step towards a novel, non-invasive, non-medication treatment for PD.
Primary Outcome
The participant will complete a 18-item comprehensive motor assessment that assesses elements of motor function including tremor, bradykinesia, and gait. The total score for this assessment ranges from 0 to 108 points, with higher scores indicating higher severity.
Interventions
- DEVICE Active LIFUP Treatment
- DEVICE Sham LIFUP Treatment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2022-06-15 |
| Est. Completion | 2024-07-31 |
| Phase | NA |
What the finished NCT04593875 record still lists
NCT04593875 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Active LIFUP Treatment is the first listed.
NCT04593875 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04593875 about?
NCT04593875 is a clinical study titled "LIFUP for Treatment of Motor Deficits in Parkinson's Disease". The study will test the feasibility of using Low Intensity Focused Ultrasound Pulsation (LIFUP) to treat motor symptoms in Parkinson's Disease (PD). LIFUP is a new technique that can increase brain activity in highly specific target areas and is MRI compatible. Thus, in real-time, it is possible to ...
What is the current status of trial NCT04593875?
This trial is currently completed. It is a NA study. The enrollment target is 31 participants. The study started on 2022-06-15. Estimated completion is 2024-07-31.
What interventions are being tested in trial NCT04593875?
The interventions under investigation include: Active LIFUP Treatment (DEVICE), Sham LIFUP Treatment (DEVICE).
Who is sponsoring clinical trial NCT04593875?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04593875's enrollment target sits among peer trials
31 1592nd of 2000 higher than 408 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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