Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04578756 · ClinicalTrials.gov registry record · Phase 3

Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder

A Phase 3 study of Schizophrenia and Bipolar I Disorder, sponsored by AbbVie.

Completed
Registry status
Phase 3
Development phase
310
Enrollment target
20
Study locations

NCT04578756 is a Phase 3 study of Schizophrenia and Bipolar I Disorder that has completed, run by AbbVie. The registered enrollment target is 310 participants, above the 218-participant average among 315 other Schizophrenia trials with a reported enrollment target (42% higher). The trial reports 20 study locations across 4 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04578756, a Phase 3 study of Schizophrenia and Bipolar I Disorder, has completed, sponsored by AbbVie.

COMPLETED
Registry status
Phase 3
Development phase
310 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to evaluate the long-term safety and tolerability of cariprazine in the treatment of pediatric participants with schizophrenia, bipolar I disorder, or autism spectrum disorder (ASD) and to establish the benefit-risk profile of long-term treatment in this population.

Interventions

  • DRUG Cariprazine Flexible Dose

Study Locations (20)

Florida

  • D&H Doral Research Center-Doral /ID# 255459 - Doral
  • Sarkis Clinical Trials /ID# 236893 - Gainesville
  • Galiz Research- Palmetto Medical Plaza /ID# 236277 - Hialeah
  • Advanced Research Institute of Miami /ID# 242505 - Homestead
  • Duplicate_Sandhill Research LLC /ID# 251239 - Lake Mary
  • Columbus Clinical Services, Llc /Id# 234281 - Miami
  • G+C Research Group, LLC /ID# 261398 - Miami
  • Florida Research Center, Inc. /ID# 236515 - Miami
  • Links Clinical Trials /ID# 240975 - Miami
  • South Florida Research Ph I-IV /ID# 237453 - Miami Springs
  • K2 Medical Research - Orlando - South Orlando Avenue /ID# 257528 - Orlando

California

  • Advanced Research Center /ID# 241903 - Anaheim
  • Duplicate_Alliance for Research - Long Beach /ID# 236261 - Long Beach
  • CHOC Children's Hospital /ID# 251019 - Orange
  • ATP Clinical Research- Orange /ID# 257095 - Orange
  • Prospective Research Innovations Inc /ID# 236098 - Rancho Cucamonga
  • University of California, San Diego Department of Psychiatry /ID# 236466 - San Diego
  • Pacific Clinical Research Management Group /ID# 234377 - Upland

Alabama

  • Harmonex Neuroscience Research /ID# 234938 - Dothan

Arkansas

  • Pillar Clinical Research /ID# 236434 - Bentonville

Trial Details

FieldValue
Enrollment Target 310 participants
Start Date 2021-02-01
Est. Completion 2025-10-06
Phase Phase 3

Sponsor

AbbVie

526 total trials

What the Registry Record Tells You About NCT04578756

The ClinicalTrials.gov registry entry for NCT04578756 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 310 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 218-participant average among 315 other Schizophrenia trials with a reported enrollment target (42% higher). The listed sponsor is AbbVie, which has 526 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Schizophrenia appearing as the primary indexed condition, and to 1 intervention - of which Cariprazine Flexible Dose is the first listed.

NCT04578756 reports 20 study locations spanning 4 distinct geographic areas - top geographies include Florida, California, Alabama.

Frequently Asked Questions

What is clinical trial NCT04578756 about?

NCT04578756 is a clinical study titled "Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder". The purpose of this study is to evaluate the long-term safety and tolerability of cariprazine in the treatment of pediatric participants with schizophrenia, bipolar I disorder, or autism spectrum disorder (ASD) and to establish the benefit-risk profile of long-term treatment in this population.

What is the current status of trial NCT04578756?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 310 participants. The study started on 2021-02-01. Estimated completion is 2025-10-06.

What conditions does trial NCT04578756 study?

This clinical trial studies the following conditions: Schizophrenia, Bipolar I Disorder, Autism Spectrum Disorder (ASD).

What interventions are being tested in trial NCT04578756?

The interventions under investigation include: Cariprazine Flexible Dose (DRUG).

Who is sponsoring clinical trial NCT04578756?

This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04578756 being conducted?

This trial has 20 study locations across Alabama, Arkansas, California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Schizophrenia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.