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NCT04574635 · ClinicalTrials.gov registry record

Human Papilloma Virus (HPV) Circulating Tumor DNA (ctDNA) in Cervical Cancer

A clinical trial of Cervical Adenosquamous Carcinoma and Recurrent Cervical Carcinoma, sponsored by Mayo Clinic.

Active
Registry status
18
Enrollment target
2
Study locations

NCT04574635: Active study of Cervical Adenosquamous Carcinoma and Recurrent Cervical Carcinoma, sponsored by Mayo Clinic.

NCT04574635 is a study of Cervical Adenosquamous Carcinoma and Recurrent Cervical Carcinoma that is active but no longer recruiting, run by Mayo Clinic. The registered enrollment target is 18 participants, below the 113-participant average among 13 other Cervical Adenosquamous Carcinoma trials with a reported enrollment target (84% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04574635, a study of Cervical Adenosquamous Carcinoma and Recurrent Cervical Carcinoma, is active but no longer recruiting, sponsored by Mayo Clinic.

ACTIVE NOT RECRUITING
Registry status
18 participants
Enrollment target
2
Study locations

Study Summary

This study collects blood samples to determine if the DNA of HPV that causes cervical cancer can be detected in patients with cervical cancer that is new (primary), has come back (recurrent), or has spread to other places in the body (metastatic) and are undergoing treatment with surgery, radiotherapy, chemotherapy, and/or immunotherapy. Researchers may use this information to predict response (good or bad) of the cervical cancer to treatment and detect recurrent cancer sooner.

Primary Outcome

The proportion will be reported along with the exact 95% binomial confidence interval. Additionally will report the mean standard deviation and median interquartile range ctDNA post-treatment in these patients.

Interventions

  • PROCEDURE Biospecimen Collection

Study Locations (2)

Minnesota

  • University of Minnesota - Minneapolis
  • Mayo Clinic in Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2020-11-17
Est. Completion 2027-11-30
Mayo Clinic

2,844 total trials

What the registry record for NCT04574635 still lists

NCT04574635 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 113-participant average among 13 other Cervical Adenosquamous Carcinoma trials with a reported enrollment target (84% lower).

The record links to 10 conditions, with Cervical Adenosquamous Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which Biospecimen Collection is the first listed.

NCT04574635 reports a single indexed study location in Minnesota.

Frequently Asked Questions

What is clinical trial NCT04574635 about?

NCT04574635 is a clinical study titled "Human Papilloma Virus (HPV) Circulating Tumor DNA (ctDNA) in Cervical Cancer". This study collects blood samples to determine if the DNA of HPV that causes cervical cancer can be detected in patients with cervical cancer that is new (primary), has come back (recurrent), or has spread to other places in the body (metastatic) and are undergoing treatment with surgery, radiothera...

What is the current status of trial NCT04574635?

This trial is currently active not recruiting. The enrollment target is 18 participants. The study started on 2020-11-17. Estimated completion is 2027-11-30.

What conditions does trial NCT04574635 study?

This clinical trial studies the following conditions: Cervical Adenosquamous Carcinoma, Recurrent Cervical Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Metastatic Cervical Carcinoma, Stage IB Cervical Cancer FIGO 2018.

What interventions are being tested in trial NCT04574635?

The interventions under investigation include: Biospecimen Collection (PROCEDURE).

Who is sponsoring clinical trial NCT04574635?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04574635 being conducted?

This trial has 2 study locations across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cervical Adenosquamous Carcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04574635's enrollment target sits among peer trials

18 13th of 13 higher than 1 of 13 other Cervical Adenosquamous Carcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cervical Adenosquamous Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04574635, the US trial registry maintained by the National Library of Medicine. NCT04574635 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.