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NCT04488744 · ClinicalTrials.gov registry record · Early Phase 1

Smoking by IV Pulsed Nicotine

A Early Phase 1 study of Smoking Cessation, sponsored by Yale University.

Completed
Registry status
Early Phase 1
Development phase
13
Enrollment target
1
Study location

NCT04488744 is a Early Phase 1 study of Smoking Cessation that has completed, run by Yale University. The registered enrollment target is 13 participants, below the 475-participant average among 188 other Smoking Cessation trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04488744, a Early Phase 1 study of Smoking Cessation, has completed, sponsored by Yale University.

COMPLETED
Registry status
Early Phase 1
Development phase
13 participants
Enrollment target
1
Study location

Study Summary

To establish a dose-effect curve for nicotine's abuse potential as a function of nicotine dose and delivery rate. Pulsed IV nicotine administration will be used as it closely matches nicotine delivery by inhaled tobacco use.

Conditions Studied

Interventions

  • DRUG Nicotine 0.2mcg/kg/s and 1.0mcg/kg/s

Study Locations (1)

Connecticut

  • Veterans Affairs Hospital - West Haven

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2019-11-15
Est. Completion 2021-05-31
Phase Early Phase 1

Sponsor

Yale University

1,492 total trials

What the Registry Record Tells You About NCT04488744

The ClinicalTrials.gov registry entry for NCT04488744 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 13 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 475-participant average among 188 other Smoking Cessation trials with a reported enrollment target (97% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Smoking Cessation appearing as the primary indexed condition, and to 1 intervention - of which Nicotine 0.2mcg/kg/s and 1.0mcg/kg/s is the first listed.

NCT04488744 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT04488744 about?

NCT04488744 is a clinical study titled "Smoking by IV Pulsed Nicotine". To establish a dose-effect curve for nicotine's abuse potential as a function of nicotine dose and delivery rate. Pulsed IV nicotine administration will be used as it closely matches nicotine delivery by inhaled tobacco use.

What is the current status of trial NCT04488744?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 13 participants. The study started on 2019-11-15. Estimated completion is 2021-05-31.

What conditions does trial NCT04488744 study?

This clinical trial studies the following conditions: Smoking Cessation.

What interventions are being tested in trial NCT04488744?

The interventions under investigation include: Nicotine 0.2mcg/kg/s and 1.0mcg/kg/s (DRUG).

Who is sponsoring clinical trial NCT04488744?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04488744 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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