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NCT04488744 · ClinicalTrials.gov registry record · Early Phase 1
Smoking by IV Pulsed Nicotine
A Early Phase 1 study of Smoking Cessation, sponsored by Yale University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 13
- Enrollment target
- 1
- Study location
NCT04488744: Completed Early Phase 1 study of Smoking Cessation, sponsored by Yale University.
NCT04488744 is a Early Phase 1 study of Smoking Cessation that has completed, run by Yale University. The registered enrollment target is 13 participants, below the 475-participant average among 188 other Smoking Cessation trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04488744, a Early Phase 1 study of Smoking Cessation, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 13 participants
- Enrollment target
- 1
- Study location
Study Summary
To establish a dose-effect curve for nicotine's abuse potential as a function of nicotine dose and delivery rate. Pulsed IV nicotine administration will be used as it closely matches nicotine delivery by inhaled tobacco use.
Primary Outcome
the dose-effect curves of nicotine dose and delivery rate in heart rate
Conditions Studied
Interventions
- DRUG Nicotine 0.2mcg/kg/s and 1.0mcg/kg/s
Study Locations (1)
Connecticut
- Veterans Affairs Hospital - West Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2019-11-15 |
| Est. Completion | 2021-05-31 |
| Phase | Early Phase 1 |
What the finished NCT04488744 record still lists
NCT04488744 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 475-participant average among 188 other Smoking Cessation trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Smoking Cessation appearing as the primary indexed condition, and to 1 intervention - of which Nicotine 0.2mcg/kg/s and 1.0mcg/kg/s is the first listed.
NCT04488744 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT04488744 about?
NCT04488744 is a clinical study titled "Smoking by IV Pulsed Nicotine". To establish a dose-effect curve for nicotine's abuse potential as a function of nicotine dose and delivery rate. Pulsed IV nicotine administration will be used as it closely matches nicotine delivery by inhaled tobacco use.
What is the current status of trial NCT04488744?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 13 participants. The study started on 2019-11-15. Estimated completion is 2021-05-31.
What conditions does trial NCT04488744 study?
This clinical trial studies the following conditions: Smoking Cessation.
What interventions are being tested in trial NCT04488744?
The interventions under investigation include: Nicotine 0.2mcg/kg/s and 1.0mcg/kg/s (DRUG).
Who is sponsoring clinical trial NCT04488744?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04488744 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Smoking Cessation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04488744's enrollment target sits among peer trials
13 184th of 188 higher than 5 of 188 other Smoking Cessation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking Cessation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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