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NCT04482686 · ClinicalTrials.gov registry record · Phase 1

Trial of Combination Therapy to Treat COVID-19 Infection

A Phase 1 study, sponsored by ProgenaBiome.

Completed
Registry status
Phase 1
Development phase
31
Enrollment target

NCT04482686: Completed Phase 1 study, sponsored by ProgenaBiome.

NCT04482686 is a Phase 1 study that has completed, run by ProgenaBiome. The registered enrollment target is 31 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (48% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04482686, a Phase 1 study, has completed, sponsored by ProgenaBiome.

COMPLETED
Registry status
Phase 1
Development phase
31 participants
Enrollment target

Study Summary

In this trial patients will be treated with either a combination of therapies to treat COVID-19 or a placebo. Treatment will last 10 days, and patients will be followed for 6 months.

Primary Outcome

Time to negative RT-PRC result indicating that patient is no longer infective

Interventions

  • DRUG Ivermectin
  • DIETARY_SUPPLEMENT Vitamin D3
  • DIETARY_SUPPLEMENT Vitamin C
  • DRUG Doxycycline Hcl
  • DIETARY_SUPPLEMENT Zinc

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2020-12-09
Est. Completion 2022-07-15
Phase Phase 1
ProgenaBiome

8 total trials

What the finished NCT04482686 record still lists

NCT04482686 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (48% lower).

The record links to 0 conditions, and to 5 interventions - of which Ivermectin is the first listed.

NCT04482686 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04482686 about?

NCT04482686 is a clinical study titled "Trial of Combination Therapy to Treat COVID-19 Infection". In this trial patients will be treated with either a combination of therapies to treat COVID-19 or a placebo. Treatment will last 10 days, and patients will be followed for 6 months.

What is the current status of trial NCT04482686?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2020-12-09. Estimated completion is 2022-07-15.

What interventions are being tested in trial NCT04482686?

The interventions under investigation include: Ivermectin (DRUG), Vitamin D3 (DIETARY_SUPPLEMENT), Vitamin C (DIETARY_SUPPLEMENT), Doxycycline Hcl (DRUG), Zinc (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT04482686?

This trial is sponsored by ProgenaBiome, which has 8 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04482686's enrollment target sits among peer trials

31 1322nd of 2000 higher than 669 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04482686, the US trial registry maintained by the National Library of Medicine. NCT04482686 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.