Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04446299 · ClinicalTrials.gov registry record · Phase 3
Study 301: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
A Phase 3 study of Colonoscopy, sponsored by Braintree Laboratories.
- Completed
- Registry status
- Phase 3
- Development phase
- 519
- Enrollment target
- 20
- Study locations
NCT04446299: Completed Phase 3 study of Colonoscopy, sponsored by Braintree Laboratories.
NCT04446299 is a Phase 3 study of Colonoscopy that has completed, run by Braintree Laboratories. The registered enrollment target is 519 participants, roughly in line with the 476-participant average among 20 other Colonoscopy trials with a reported enrollment target. The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04446299, a Phase 3 study of Colonoscopy, has completed, sponsored by Braintree Laboratories.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 519 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to compare the safety and efficacy of BLI4900 bowel preparation to an FDA-approved control as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
Primary Outcome
Successful bowel preparation is defined as a preparation rated as Excellent or Good by the blinded endoscopist on a 4 point scale (Excellent, Good, Fair, Poor).
Conditions Studied
Interventions
- DRUG Bowel Prep
Study Locations (20)
Florida
- 301 Research Site 16 - Clearwater
- 301 Research Site 12 - Jacksonville
- 301 Research Site 9 - Palm Harbor
- 301 Research Site 4 - Palmetto Bay
- 301 Research Site 26 - Port Orange
- 301 Research Site 14 - St. Petersburg
- 301 Research Site 25 - Sunrise
New York
- 301 Research Site 15 - Brooklyn
- 301 Research Site 5 - Great Neck
- 301 Research Site 23 - New York
Louisiana
- 301 Research Site 3 - Monroe
- 301 Research Site 17 - Shreveport
Alabama
- 301 Research Site 18 - Huntsville
Arizona
- 301 Research Site 24 - Sun City
California
- 301 Research Site 7 - San Diego
Georgia
- 301 Research Site 2 - Decatur
Indiana
- 301 Research Site 10 - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 519 participants |
| Start Date | 2020-07-13 |
| Est. Completion | 2021-01-22 |
| Phase | Phase 3 |
What the finished NCT04446299 record still lists
NCT04446299 is an interventional study that assigns participants to a tested intervention. The registered 519 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 476-participant average among 20 other Colonoscopy trials with a reported enrollment target.
The record links to 1 condition, with Colonoscopy appearing as the primary indexed condition, and to 1 intervention - of which Bowel Prep is the first listed.
NCT04446299 names 20 study sites across 11 states, led by Florida, New York, Louisiana.
Frequently Asked Questions
What is clinical trial NCT04446299 about?
NCT04446299 is a clinical study titled "Study 301: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy". The purpose of this study is to compare the safety and efficacy of BLI4900 bowel preparation to an FDA-approved control as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
What is the current status of trial NCT04446299?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 519 participants. The study started on 2020-07-13. Estimated completion is 2021-01-22.
What conditions does trial NCT04446299 study?
This clinical trial studies the following conditions: Colonoscopy.
What interventions are being tested in trial NCT04446299?
The interventions under investigation include: Bowel Prep (DRUG).
Who is sponsoring clinical trial NCT04446299?
This trial is sponsored by Braintree Laboratories, which has 49 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04446299 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colonoscopy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04446299's enrollment target sits among peer trials
519 5th of 20 higher than 16 of 20 other Colonoscopy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colonoscopy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
A Phase III Study of the Efficacy and Safety of Remimazolam Compared to Placebo and Midazolam in Colonoscopy Patients
COMPLETED · Phase 3
-
HalfLytely Bowel Prep System for Colonoscopy
COMPLETED · Phase 3
-
BLI-800-301: BLI-800 vs an Active Control Bowel Preparation in Adult Subjects Undergoing Colonoscopy
COMPLETED · Phase 3
-
A Safety Study of 3 Different Bowel Cleansing Preparations
COMPLETED · Phase 3
-
Can Nitrous Oxide (Laughing Gas) be Used as a Sedative for GI Endoscopy Procedures?
RECRUITING · Phase 4
-
Can Overall Adenoma Detection Rate Replace Screening Adenoma Detection Rate ? Multicenter Study
RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02323581 · 520 participants · NA
Endovascular Treatment of TAAA and Aortic Arch Aneurysms Using Fenestrated and Branched Stent Grafts
- NCT04656496 · 520 participants · NA
NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors
- NCT05445778 · 520 participants · Phase 3
Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer
- NCT05498428 · 520 participants · Phase 2
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI