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NCT04430699 · ClinicalTrials.gov registry record · Phase 2

Cisplatin+Pembrolizumab+RT in Vulvar Cancer

A Phase 2 study of Vulvar Cancer and Vulvar Squamous Cell Carcinoma, sponsored by Massachusetts General Hospital.

Active
Registry status
Phase 2
Development phase
24
Enrollment target
2
Study locations

NCT04430699 is a Phase 2 study of Vulvar Cancer and Vulvar Squamous Cell Carcinoma that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 24 participants, below the 452-participant average among 17 other Vulvar Cancer trials with a reported enrollment target (95% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT04430699, a Phase 2 study of Vulvar Cancer and Vulvar Squamous Cell Carcinoma, is active but no longer recruiting, sponsored by Massachusetts General Hospital.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
24 participants
Enrollment target
2
Study locations

Study Summary

This research is being done to see how well the combination of a standard of care drug, investigational drug, and radiation therapy work against unresectable vulvar squamous cell carcinoma. This research study involves the following: * Cisplatin (standard of care drug) * Pembrolizumab (investigational drug) * Radiation Therapy (standard of care intervention)

Interventions

  • DRUG Pembrolizumab
  • DRUG Cisplatin
  • RADIATION Radiation Therapy

Study Locations (2)

Massachusetts

  • Massachusetts General Hospital Cancer Center - Boston
  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2020-07-29
Est. Completion 2028-01-30
Phase Phase 2

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT04430699

The ClinicalTrials.gov registry entry for NCT04430699 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 452-participant average among 17 other Vulvar Cancer trials with a reported enrollment target (95% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Vulvar Cancer appearing as the primary indexed condition, and to 3 interventions - of which Pembrolizumab is the first listed.

NCT04430699 reports 2 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04430699 about?

NCT04430699 is a clinical study titled "Cisplatin+Pembrolizumab+RT in Vulvar Cancer". This research is being done to see how well the combination of a standard of care drug, investigational drug, and radiation therapy work against unresectable vulvar squamous cell carcinoma. This research study involves the following: * Cisplatin (standard of care drug) * Pembrolizumab (investigati...

What is the current status of trial NCT04430699?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2020-07-29. Estimated completion is 2028-01-30.

What conditions does trial NCT04430699 study?

This clinical trial studies the following conditions: Vulvar Cancer, Vulvar Squamous Cell Carcinoma.

What interventions are being tested in trial NCT04430699?

The interventions under investigation include: Pembrolizumab (DRUG), Cisplatin (DRUG), Radiation Therapy (RADIATION).

Who is sponsoring clinical trial NCT04430699?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04430699 being conducted?

This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.