Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04419870 · ClinicalTrials.gov registry record
Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity
A clinical trial of Mitochondrial Disease, sponsored by National Human Genome Research Institute (NHGRI).
- Recruiting
- Registry status
- 400
- Enrollment target
- 1
- Study location
NCT04419870 is a study of Mitochondrial Disease that is actively recruiting participants, run by National Human Genome Research Institute (NHGRI). The registered enrollment target is 400 participants, above the 108-participant average among 5 other Mitochondrial Disease trials with a reported enrollment target (270% higher). The trial reports 1 study location across 1 state.
The verdict
NCT04419870, a study of Mitochondrial Disease, is actively recruiting participants, sponsored by National Human Genome Research Institute (NHGRI).
- RECRUITING
- Registry status
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Mitochondrial disease is a rare disorder. It can cause poor growth, developmental delays, muscle weakness, and other symptoms. The disease is usually inherited. It can be present at birth or develop later in life. Infection is a major cause of disease and death in people with this disease. Researchers want to learn more about these infections and the declining health of people who have this disease. To do this, researchers will study the DNA of people who become ill. Their DNA will be compared to the DNA of their household/family members. Objective: To learn more about how genes affect people with mitochondrial disease. Eligibility: People age 2 months and older with mitochondrial disease and their household/family members. .\<TAB\> Design: Participants will complete a questionnaire about their health history. Their medical records may be reviewed. They will give a blood sample. If the participant becomes ill, they may have a videoconference with a doctor or nurse at the NIH to perform a physical exam. They may be contacted after their illness to give updates on their health. They may be asked to give extra blood samples or complete extra questionnaires. Participants genetic data will be put into a database. The data will be labeled with a code and not their name. The data will be shared with other researchers. Participation lasts about 1 year. This may be extended if the participant is very ill.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2020-10-21 |
| Est. Completion | 2026-05-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04419870
The ClinicalTrials.gov registry entry for NCT04419870 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 108-participant average among 5 other Mitochondrial Disease trials with a reported enrollment target (270% higher). The listed sponsor is National Human Genome Research Institute (NHGRI), which has 185 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Mitochondrial Disease appearing as the primary indexed condition, and to 0 interventions.
NCT04419870 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT04419870 about?
NCT04419870 is a clinical study titled "Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity". Background: Mitochondrial disease is a rare disorder. It can cause poor growth, developmental delays, muscle weakness, and other symptoms. The disease is usually inherited. It can be present at birth or develop later in life. Infection is a major cause of disease and death in people with this disea...
What is the current status of trial NCT04419870?
This trial is currently recruiting. The enrollment target is 400 participants. The study started on 2020-10-21. Estimated completion is 2026-05-01.
What conditions does trial NCT04419870 study?
This clinical trial studies the following conditions: Mitochondrial Disease.
Who is sponsoring clinical trial NCT04419870?
This trial is sponsored by National Human Genome Research Institute (NHGRI), which has 185 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04419870 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Mitochondrial Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Validation of Nanosensor Oxygen Measurement
RECRUITING · Phase 1
-
Study of N-acetylcysteine in the Treatment of Patients With the m.3243A>G Mutation and Low Brain Glutathione Levels
RECRUITING · Phase 1
-
Mitochondrial Dysfunction in Autism Spectrum Disorder
ACTIVE NOT RECRUITING
-
Assessment of Small Fiber Neuropathy in Rare Diseases Using Sudoscan
COMPLETED · NA
-
Mechanisms of Mitochondrial Defects in Gulf War Syndrome
COMPLETED
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.