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NCT04415047 · ClinicalTrials.gov registry record · NA

The JenaValve ALIGN-AR Pivotal Trial

A NA study of Aortic Valve Disease and Aortic Valve Insufficiency, sponsored by JenaValve Technology.

Active
Registry status
NA
Development phase
180
Enrollment target
20
Study locations

NCT04415047 is a NA study of Aortic Valve Disease and Aortic Valve Insufficiency that is active but no longer recruiting, run by JenaValve Technology. The registered enrollment target is 180 participants, below the 18,605-participant average among 15 other Aortic Valve Disease trials with a reported enrollment target (99% lower). The trial reports 20 study locations across 14 states.

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The verdict

NCT04415047, a NA study of Aortic Valve Disease and Aortic Valve Insufficiency, is active but no longer recruiting, sponsored by JenaValve Technology.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
180 participants
Enrollment target
20
Study locations

Study Summary

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may include fatigue and shortness of breath. The preferred treatment for severe aortic regurgitation is aortic valve replacement surgery.

Interventions

  • DEVICE JenaValve Trilogy Heart Valve System

Study Locations (20)

California

  • Cedars Sinai Medical Center - Los Angeles
  • Scripps Hospital - San Diego
  • California Pacific Medical Center Research Institute - San Francisco

Ohio

  • The Christ Hospital - Cincinnati
  • Cleveland Clinic Foundation - Cleveland
  • Ohio Health Research Institute - Columbus

Georgia

  • Piedmont Healthcare - Atlanta
  • Emory University Hospital - Atlanta

Michigan

  • University of Michigan - Ann Arbor
  • Henry Ford Health System - Detroit

Arizona

  • TMC HealthCare & PIMA Heart - Tucson

District of Columbia

  • MedStar Washington Hospital Center - Washington D.C.

Florida

  • Morton Plant/ BayCare Health - Clearwater

Illinois

  • Cardiac Surgery Clinical Research Center Inc./ Advocate Aurora Health - Oak Lawn

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2020-05-22
Est. Completion 2028-08
Phase NA

Sponsor

JenaValve Technology

4 total trials

What the Registry Record Tells You About NCT04415047

The ClinicalTrials.gov registry entry for NCT04415047 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 18,605-participant average among 15 other Aortic Valve Disease trials with a reported enrollment target (99% lower). The listed sponsor is JenaValve Technology, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Aortic Valve Disease appearing as the primary indexed condition, and to 1 intervention - of which JenaValve Trilogy Heart Valve System is the first listed.

NCT04415047 reports 20 study locations spanning 14 distinct geographic areas - top geographies include California, Ohio, Georgia.

Frequently Asked Questions

What is clinical trial NCT04415047 about?

NCT04415047 is a clinical study titled "The JenaValve ALIGN-AR Pivotal Trial". To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aort...

What is the current status of trial NCT04415047?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2020-05-22. Estimated completion is 2028-08.

What conditions does trial NCT04415047 study?

This clinical trial studies the following conditions: Aortic Valve Disease, Aortic Valve Insufficiency, Aortic Regurgitation, Aortic Insufficiency.

What interventions are being tested in trial NCT04415047?

The interventions under investigation include: JenaValve Trilogy Heart Valve System (DEVICE).

Who is sponsoring clinical trial NCT04415047?

This trial is sponsored by JenaValve Technology, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04415047 being conducted?

This trial has 20 study locations across Arizona, California, District of Columbia, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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