Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04379414 · ClinicalTrials.gov registry record · NA

YES Study - Newly Diagnosed/Metastatic Intervention

A NA study of Breast Cancer and Symptom, Behavioral, sponsored by Dana-Farber Cancer Institute.

Active
Registry status
NA
Development phase
400
Enrollment target
1
Study location

NCT04379414: Active NA study of Breast Cancer and Symptom, Behavioral, sponsored by Dana-Farber Cancer Institute.

NCT04379414 is a NA study of Breast Cancer and Symptom, Behavioral that is active but no longer recruiting, run by Dana-Farber Cancer Institute. The registered enrollment target is 400 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04379414, a NA study of Breast Cancer and Symptom, Behavioral, is active but no longer recruiting, sponsored by Dana-Farber Cancer Institute.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
400 participants
Enrollment target
1
Study location

Study Summary

This research study is being done to monitor common symptoms and behavior, and to provide supportive care information and peer support, as well as research opportunities for young women ages of 18-39 years old who have been diagnosed with stage 0-IV stage breast cancer using a web-based portal (YES), built for smartphones, tablets, and computers.

Primary Outcome

One item regarding vaginal dryness on the BCPT will be used and grouped by moderate, quite a bit, extreme responses to define the vaginal dryness rate at 1 year. Based on historical data (from our ongoing Young Women's Breast Cancer Study), the 1-year vaginal dryness rate for the control group is assumed to be 27%. For the Phase II randomized controlled trial component of the study,it will have 85% power to detect a 10% difference in the primary endpoint with 367 patients, and would plan to recr

Interventions

  • BEHAVIORAL YES portal

Study Locations (1)

Massachusetts

  • Dana Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2020-09-16
Est. Completion 2028-03-01
Phase NA
Dana-Farber Cancer Institute

781 total trials

What the registry record for NCT04379414 still lists

NCT04379414 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (86% lower).

The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which YES portal is the first listed.

NCT04379414 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04379414 about?

NCT04379414 is a clinical study titled "YES Study - Newly Diagnosed/Metastatic Intervention". This research study is being done to monitor common symptoms and behavior, and to provide supportive care information and peer support, as well as research opportunities for young women ages of 18-39 years old who have been diagnosed with stage 0-IV stage breast cancer using a web-based portal (YES)...

What is the current status of trial NCT04379414?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 400 participants. The study started on 2020-09-16. Estimated completion is 2028-03-01.

What conditions does trial NCT04379414 study?

This clinical trial studies the following conditions: Breast Cancer, Symptom, Behavioral.

What interventions are being tested in trial NCT04379414?

The interventions under investigation include: YES portal (BEHAVIORAL).

Who is sponsoring clinical trial NCT04379414?

This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04379414 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04379414's enrollment target sits among peer trials

400 233rd of 1224 higher than 981 of 1,224 other Breast Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01665326 · 400 participants

    Determination of CRIM Status and Longitudinal Follow-up of Individuals With Pompe Disease

  • NCT02108054 · 400 participants · NA

    Behavioral and Functional Task Development, Implementation, and Testing

  • NCT02216500 · 400 participants · NA

    Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy

  • NCT02285582 · 400 participants

    International Rare Histiocytic Disorders Registry (IRHDR)

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04379414, the US trial registry maintained by the National Library of Medicine. NCT04379414 (mid enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.