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NCT04371432 · ClinicalTrials.gov registry record
Genetics of COVID-19 Susceptibility and Manifestations
A clinical trial, sponsored by National Human Genome Research Institute (NHGRI).
- Completed
- Registry status
- 721
- Enrollment target
NCT04371432: Completed study, sponsored by National Human Genome Research Institute (NHGRI).
NCT04371432 is a clinical trial that has completed, run by National Human Genome Research Institute (NHGRI). The registered enrollment target is 721 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04371432 has completed, sponsored by National Human Genome Research Institute (NHGRI).
- COMPLETED
- Registry status
- 721 participants
- Enrollment target
Study Summary
Background: Coronavirus 2019 (COVID-19, or SARS-CoV-2) is a serious public health problem, and genetics may play a role in how serious the illness becomes in certain people. Genes are the instructions that our body uses to grow and develop. Variations in our genes can cause medical conditions and may be the reason why some people get sicker than others. Objective: This study aims to learn more about the genetic contributions to the severity of COVID-19. We hope to use this information to develop therapies that reduce the severity of COVID-19 symptoms in some people. Eligibility: Anyone located in the United States who has tested positive for SARS-CoV-2 infection may be eligible to join (including NIH staff). Design: Participants will complete a questionnaire about their health history and COVID-19 symptoms. Participants will give a blood or saliva sample. It will be about 2 tablespoons of blood, or we will send a saliva collection kit. Researchers will use this blood or saliva sample to study the participant s DNA. The data about participants genes will be stored in a large database. The database will be shared with other qualified researchers who are trying to learn about COVID-19. Participants names and other personal details will not be shared. Instead, the data will be labeled with a code. Participants may be contacted by study team members for up to a year after they join the study.
Primary Outcome
Identify common and rare germline variants associated with host susceptibility to severe or fatal COVID-19 disease using a case-case design.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 721 participants |
| Start Date | 2020-05-05 |
| Est. Completion | 2024-12-15 |
What the finished NCT04371432 record still lists
NCT04371432 is an observational study that tracks outcomes without assigning an intervention. The registered 721 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT04371432 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04371432 about?
NCT04371432 is a clinical study titled "Genetics of COVID-19 Susceptibility and Manifestations". Background: Coronavirus 2019 (COVID-19, or SARS-CoV-2) is a serious public health problem, and genetics may play a role in how serious the illness becomes in certain people. Genes are the instructions that our body uses to grow and develop. Variations in our genes can cause medical conditions and m...
What is the current status of trial NCT04371432?
This trial is currently completed. The enrollment target is 721 participants. The study started on 2020-05-05. Estimated completion is 2024-12-15.
Who is sponsoring clinical trial NCT04371432?
This trial is sponsored by National Human Genome Research Institute (NHGRI), which has 185 total clinical trials registered on ClinicalTrials.gov.
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