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NCT04370587 · ClinicalTrials.gov registry record · Phase 1

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

A Phase 1 study of Melanoma and Solid Tumor, sponsored by ImmVira Pharma Co..

Recruiting
Registry status
Phase 1
Development phase
30
Enrollment target
9
Study locations

NCT04370587 is a Phase 1 study of Melanoma and Solid Tumor that is actively recruiting participants, run by ImmVira Pharma Co.. The registered enrollment target is 30 participants, below the 706-participant average among 266 other Melanoma trials with a reported enrollment target (96% lower). The trial reports 9 study locations across 6 states.

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The verdict

NCT04370587, a Phase 1 study of Melanoma and Solid Tumor, is actively recruiting participants, sponsored by ImmVira Pharma Co..

RECRUITING
Registry status
Phase 1
Development phase
30 participants
Enrollment target
9
Study locations

Study Summary

This is a Phase 1/2a, open-label, study to evaluate the safety and preliminary efficacy of intratumoral T3011 given alone and in combination with intravenous pembrolizumab in partients with advanced or metastatic solid tumors.

Interventions

  • BIOLOGICAL T3011
  • COMBINATION_PRODUCT T3011 + pembrolizumab

Study Locations (9)

Other

  • Southern Oncology - Bedford Park
  • Peninsula & South Eastern Haematology and Oncology Group - Frankston
  • The Alfred - Melbourne

Massachusetts

  • Massachusetts General Hospital - Boston
  • Dana Farber Cancer Institute - Boston

Arizona

  • Banner MD Anderson Cancer Center - Gilbert

Pennsylvania

  • University of Pittsburgh Medical Center - Pittsburgh

Texas

  • Mary Crowley Cancer Research - Dallas

Virginia

  • Virginia Cancer Specialists - Fairfax

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2020-09-17
Est. Completion 2027-01-10
Phase Phase 1

Sponsor

ImmVira Pharma Co.

2 total trials

What the Registry Record Tells You About NCT04370587

The ClinicalTrials.gov registry entry for NCT04370587 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 706-participant average among 266 other Melanoma trials with a reported enrollment target (96% lower). The listed sponsor is ImmVira Pharma Co., which has 2 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with Melanoma appearing as the primary indexed condition, and to 2 interventions - of which T3011 is the first listed.

NCT04370587 reports 9 study locations spanning 6 distinct geographic areas - top geographies include Other, Massachusetts, Arizona.

Frequently Asked Questions

What is clinical trial NCT04370587 about?

NCT04370587 is a clinical study titled "A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors". This is a Phase 1/2a, open-label, study to evaluate the safety and preliminary efficacy of intratumoral T3011 given alone and in combination with intravenous pembrolizumab in partients with advanced or metastatic solid tumors.

What is the current status of trial NCT04370587?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2020-09-17. Estimated completion is 2027-01-10.

What conditions does trial NCT04370587 study?

This clinical trial studies the following conditions: Melanoma, Solid Tumor, Sarcoma, NSCLC, Squamous Cell Carcinoma.

What interventions are being tested in trial NCT04370587?

The interventions under investigation include: T3011 (BIOLOGICAL), T3011 + pembrolizumab (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT04370587?

This trial is sponsored by ImmVira Pharma Co., which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04370587 being conducted?

This trial has 9 study locations across Arizona, Massachusetts, Pennsylvania, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.