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NCT04284540 · ClinicalTrials.gov registry record · NA
Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma
A NA study, sponsored by Icahn School of Medicine at Mount Sinai.
- Completed
- Registry status
- NA
- Development phase
- 37
- Enrollment target
NCT04284540: Completed NA study, sponsored by Icahn School of Medicine at Mount Sinai.
NCT04284540 is a NA study that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 37 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04284540, a NA study, has completed, sponsored by Icahn School of Medicine at Mount Sinai.
- COMPLETED
- Registry status
- NA
- Development phase
- 37 participants
- Enrollment target
Study Summary
The purpose of this research study is to investigate a shorter radiation treatment schedule for head and neck cancers in patients 70 years of age and older. Standard radiation treatment for head and neck patients normally requires that the patient travel to the hospital daily for 6-7 weeks to receive radiation treatment 5 days per week. This long course of radiation can lead to significant side effects resulting in some people being unable to complete the course of treatment. If this happens, and there are gaps in the radiation treatment, this can lead to worse outcomes.
Primary Outcome
For the adjuvant cohort: LRC will be defined as absence of disease on imaging or no clinical evidence of disease. For the definitive cohort: LRC will be defined as regression in size or disappearance of primary tumor and/or lymph nodes on imaging or clinical examination.
Interventions
- RADIATION Adjuvant hypofractionation
- RADIATION Definitive Hypofractionation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2019-07-01 |
| Est. Completion | 2025-06-12 |
| Phase | NA |
What the finished NCT04284540 record still lists
NCT04284540 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Adjuvant hypofractionation is the first listed.
NCT04284540 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04284540 about?
NCT04284540 is a clinical study titled "Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma". The purpose of this research study is to investigate a shorter radiation treatment schedule for head and neck cancers in patients 70 years of age and older. Standard radiation treatment for head and neck patients normally requires that the patient travel to the hospital daily for 6-7 weeks to recei...
What is the current status of trial NCT04284540?
This trial is currently completed. It is a NA study. The enrollment target is 37 participants. The study started on 2019-07-01. Estimated completion is 2025-06-12.
What interventions are being tested in trial NCT04284540?
The interventions under investigation include: Adjuvant hypofractionation (RADIATION), Definitive Hypofractionation (RADIATION).
Who is sponsoring clinical trial NCT04284540?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04284540's enrollment target sits among peer trials
37 1540th of 2000 higher than 460 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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