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NCT04278521 · ClinicalTrials.gov registry record · NA
Mechanism of Action of Transcranial Magnetic Stimulation
A NA study of Depression and Major Depressive Disorder, sponsored by Massachusetts General Hospital.
- Active
- Registry status
- NA
- Development phase
- 54
- Enrollment target
- 1
- Study location
NCT04278521: Active NA study of Depression and Major Depressive Disorder, sponsored by Massachusetts General Hospital.
NCT04278521 is a NA study of Depression and Major Depressive Disorder that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 54 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04278521, a NA study of Depression and Major Depressive Disorder, is active but no longer recruiting, sponsored by Massachusetts General Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 54 participants
- Enrollment target
- 1
- Study location
Study Summary
This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.
Primary Outcome
Measured by Magnetic Resonance Imaging
Conditions Studied
Interventions
- DEVICE Transcranial Magnetic Stimulation
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2011-11 |
| Est. Completion | 2026-06 |
| Phase | NA |
What the registry record for NCT04278521 still lists
NCT04278521 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Transcranial Magnetic Stimulation is the first listed.
NCT04278521 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04278521 about?
NCT04278521 is a clinical study titled "Mechanism of Action of Transcranial Magnetic Stimulation". This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.
What is the current status of trial NCT04278521?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 54 participants. The study started on 2011-11. Estimated completion is 2026-06.
What conditions does trial NCT04278521 study?
This clinical trial studies the following conditions: Depression, Major Depressive Disorder.
What interventions are being tested in trial NCT04278521?
The interventions under investigation include: Transcranial Magnetic Stimulation (DEVICE).
Who is sponsoring clinical trial NCT04278521?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04278521 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04278521's enrollment target sits among peer trials
54 457th of 679 higher than 219 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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