Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04275700 · ClinicalTrials.gov registry record · NA
Study of PRP in Women With Evidence of Diminished Ovarian Reserve
A NA study of Diminished Ovarian Reserve and Ovarian Failure, sponsored by Center for Human Reproduction.
- Completed
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT04275700: Completed NA study of Diminished Ovarian Reserve and Ovarian Failure, sponsored by Center for Human Reproduction.
NCT04275700 is a NA study of Diminished Ovarian Reserve and Ovarian Failure that has completed, run by Center for Human Reproduction. The registered enrollment target is 80 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04275700, a NA study of Diminished Ovarian Reserve and Ovarian Failure, has completed, sponsored by Center for Human Reproduction.
- COMPLETED
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The hypothesis of the study is that ovaries of women with a history of poor response to ovulation induction may benefit from exposure to growth factors known to be present in Platelet Rich Plasma (PRP). Since even ovaries from women with poor response still contain primordial follicles (which, however, no longer undergo recruitment), it is hoped that PRP injections into ovaries will activate follicular recruitment pathways and, subsequently, result in follicle growth. Should such growth be observed, follicles will be supported with routine daily gonadotropin stimulation until hCG trigger.
Primary Outcome
Emergence of new ovarian follicles greater than 4 mm in average diameter as measured using pelvic sonography with evidence of change estradiol serum estradiol levels as measured using a immuno assay.
Conditions Studied
Interventions
- PROCEDURE A-PRP
Study Locations (1)
New York
- Center For Human Reproduction - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2018-10-01 |
| Est. Completion | 2024-09-01 |
| Phase | NA |
What the finished NCT04275700 record still lists
NCT04275700 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 2 conditions, with Diminished Ovarian Reserve appearing as the primary indexed condition, and to 1 intervention - of which A-PRP is the first listed.
NCT04275700 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT04275700 about?
NCT04275700 is a clinical study titled "Study of PRP in Women With Evidence of Diminished Ovarian Reserve". The hypothesis of the study is that ovaries of women with a history of poor response to ovulation induction may benefit from exposure to growth factors known to be present in Platelet Rich Plasma (PRP). Since even ovaries from women with poor response still contain primordial follicles (which, howev...
What is the current status of trial NCT04275700?
This trial is currently completed. It is a NA study. The enrollment target is 80 participants. The study started on 2018-10-01. Estimated completion is 2024-09-01.
What conditions does trial NCT04275700 study?
This clinical trial studies the following conditions: Diminished Ovarian Reserve, Ovarian Failure.
What interventions are being tested in trial NCT04275700?
The interventions under investigation include: A-PRP (PROCEDURE).
Who is sponsoring clinical trial NCT04275700?
This trial is sponsored by Center for Human Reproduction, which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04275700 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Diminished Ovarian Reserve
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04275700's enrollment target sits among peer trials
80 994th of 2000 higher than 941 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01243931 · 80 participants · NA
Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy
- NCT01659203 · 80 participants · Phase 1
Proton or Photon RT for Retroperitoneal Sarcomas
- NCT01803451 · 80 participants · Early Phase 1
Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
- NCT01964859 · 80 participants · Phase 2
Feasibility Study for Fibroblast Autologous Skin Grafts
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI